During the last years a considerable therapeutic progress in melanoma patients with the
RAF V600E mutation via RAF/MEK pathway inhibition and immuno-therapeutic modalities …

Melanoma is a high-grade, poorly differentiated malignant tumor of pigment-producing cells
(melanocytes), accounting for more than 70% of the skin cancer related deaths. Although …

Melanoma is a very aggressive skin cancer with increasing incidence worldwide.
MicroRNAs are small, noncoding RNAs that regulate gene expression of targeted gene (s) …

Acquired tumor resistance to cancer therapies poses major challenges in the treatment of
cancers including melanoma. Among several signaling pathways or factors that affect …

MicroRNAs (miRNAs) are small non-coding RNAs with regulatory roles, which are involved
in a broad spectrum of physiological and pathological processes, including cancer. A …

Melanoma is a highly aggressive and deadly skin cancer. Early intervention correlates with
nearly 100% patient survival, but greater than 80% mortality is associated with advanced …

Melanoma is the most dangerous form of skin cancer, being largely resistant to conventional
therapies at advanced stages. Understanding the molecular mechanisms behind this …

Melanoma is a life-threatening malignancy with poor prognosis and a relatively high burden
of mortality in advanced stages. The efficacy of current available therapeutic strategies is …

Melanoma is the deadliest form of skin cancer. Current challenges facing the management
of melanoma include accurate prediction of individuals who will respond to adjuvant …

Melanoma is the leading cause of skin cancer deaths in the United States, and its incidence
has been rising steadily for the past 30 years (Aftab, Dinger, & Perera, 2014). A more …