Lung cancer protein expression profiles of smokers and non-smokers

T Efferth, R Koomägi, J Mattern… - Cancer Genomics & …, 2004 - cgp.iiarjournals.org
Epidemiological studies have established a causal relationship between cigarette smoking
and respiratory tract cancer. The knowledge about the interaction of tobacco constituents …

Differences in protein expression patterns in lung adenocarcinomas arising in never versus ever smokers

C Behrens, H Lin, M Nunez, P Yuan, L Solis, MG Raso… - Cancer Research, 2010 - AACR
Background. Approximately 25% of lung cancer cases worldwide, mostly adenocarcinomas,
are not attributable to tobacco use. Despite that some striking differences have been …

[HTML][HTML] Molecular profile of lung cancer in never smokers

J Subramanian, R Govindan - European Journal of Cancer Supplements, 2013 - Elsevier
Tobacco smoking is the most common cause of lung cancer, but approximately 10–25% of
patients with lung cancer are life-long never smokers. The cause of lung cancer in never …

Bronchial airway gene expression in smokers with lung or head and neck cancer

E Van Dyck, PV Nazarov, A Muller, N Nicot… - Cancer …, 2014 - Wiley Online Library
Cigarette smoking is the major cause of cancers of the respiratory tract, including non‐small
cell lung cancer (NSCLC) and head and neck cancer (HNC). In order to better understand …

Molecular changes in smoking-related lung cancer

S Begum - Expert Review of Molecular Diagnostics, 2012 - Taylor & Francis
To elucidate the effect of cigarette smoke on developing lung cancer among individuals,
numerous genetic and epigenetic factors related to cigarette smoke-induced lung cancers …

Serum Biomarker of Lung Carcinogenesis Induced by Cigarette Smoking

T Okano, A Gemma, S Kudoh - Journal of Nippon Medical School, 2008 - jstage.jst.go.jp
Background There are several risk factors for lung cancer, including environmental and
occupational factors, and the genetic predisposition of the individual. Cigarette smoking is …

Proteomic approach to biomarker discovery in cancer tissue from lung adenocarcinoma among nonsmoking Chinese women in Hong Kong

JSK Au, WCS Cho, T Yip, SCK Law - Cancer investigation, 2008 - Taylor & Francis
Half of the female patients with adenocarcinoma in East Asia are never-smokers. Proteomic
analysis of tumor tissue may throw important light on the pathogenesis of this interesting …

Global Analysis of Protein Expression in A549 Cells After Prolonged Nicotine Exposure by Using Label-free Quantification

S Komkleow, C Weeraphan… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Lung cancer is the leading cause of cancer death worldwide. Cigarette
smoke is the most important risk factor for cancer development. Growing evidence indicates …

[HTML][HTML] Identification of prognostic biomarkers of smoking-related lung cancer

C Liang, W Pan, Z Zhou, X Liu - Journal of Thoracic Disease, 2024 - jtd.amegroups.org
Background: The early diagnosis and effective prognostic treatment measures for lung
cancer are still limited, leading to a 5-year survival rate of less than 15% for these patients …

[HTML][HTML] Pathogenic mechanisms of lung adenocarcinoma in smokers and non-smokers determined by gene expression interrogation

Y Hu, G Chen - Oncology Letters, 2015 - spandidos-publications.com
Cigarette smoking is the leading risk factor for lung cancer, which accounts for the highest
number of cancer‑related mortalities worldwide in men and women. Individuals with a …