Synergism of adipocytokine profile and ADIPOQ/TNF-α polymorphisms in NAFLD-associated MetS predict colorectal liver metastases outgrowth

R Divella, A Daniele, R De Luca… - Cancer genomics & …, 2019 - cgp.iiarjournals.org
Background/Aim: The aim of this study was to evaluate whether the altered profile of
adipocytokine and genetic fingerprint in NAFLD-associated metabolic syndrome “cluster” …

[HTML][HTML] ADIPOQ rs266729 G/C gene polymorphism and plasmatic adipocytokines connect metabolic syndrome to colorectal cancer

R Divella, A Daniele, A Mazzocca, I Abbate… - Journal of …, 2017 - ncbi.nlm.nih.gov
Background: ADIPOQ gene, which encode for Adiponectin (APN), is sited on chromosome
3q27 and linked to a susceptibility locus for metabolic syndrome (MetS). The ADIPOQ …

[HTML][HTML] The relationship between nonalcoholic fatty liver disease and colorectal cancer: the future challenges and outcomes of the metabolic syndrome

SO Muhidin, AA Magan, KA Osman, S Syed… - Journal of …, 2012 - hindawi.com
Nonalcoholic fatty liver disease (NAFLD) is closely related to insulin resistance, metabolic
syndrome, obesity, type 2 diabetes, and dyslipidaemia. Obesity and metabolic syndrome are …

[HTML][HTML] Adiponectin, leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD

V Marques, MB Afonso, N Bierig… - Frontiers in …, 2021 - frontiersin.org
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to …

[HTML][HTML] Key genes associated with non-alcoholic fatty liver disease and hepatocellular carcinoma with metabolic risk factors

F Yang, B Ni, Q Lian, X Qiu, Y He, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) has become the world's primary cause of
cancer death. Obesity, hyperglycemia, and dyslipidemia are all illnesses that are part of the …

[HTML][HTML] Association of adiponectin rs1501299 and rs266729 gene polymorphisms with nonalcoholic fatty liver disease

M Hashemi, HH Bojd, EE Nasab, A Bahari… - Hepatitis …, 2013 - ncbi.nlm.nih.gov
Background Genetic and environmental factors are important for the development of
nonalcoholic fatty liver disease (NAFLD). Adiponectin is a white and brown adipose tissue …

[HTML][HTML] Association of Adiponectin gene polymorphisms and nonalcoholic fatty liver disease

HJ Li, CP Li, C Zhang, XL Zhong… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Objective: To investigate the correlation between Adiponectin gene polymorphisms and the
genetic susceptibility of nonalcoholic fatty liver disease (NAFLD). Methods: 357 NAFLD …

[HTML][HTML] Single nucleotide polymorphism of genes associated with metabolic fatty liver disease

T Mu, L Peng, X Xie, H He, Q Shao, X Wang… - Journal of …, 2022 - hindawi.com
Aims. The present study aimed to reveal the relationship between single nucleotide
polymorphism (SNP) of PNPLA3, TM6SF2, MBOAT7, GATAD2A, and STAT3 genes and …

Causal association of nonalcoholic fatty liver disease with 22 extrahepatic cancers: A Mendelian randomization study

J Xie, H Gao, C Liu, Y Pan, C Xu, L Xu - Hepatology Research, 2024 - Wiley Online Library
Aim It is unclear whether nonalcoholic fatty liver disease (NAFLD) acts as a direct
contributing factor to multiple extrahepatic cancers. We aimed to systematically investigate …

[HTML][HTML] Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity

MGM Wolfs, N Gruben, SS Rensen, FJ Verdam… - Nutrition & …, 2015 - nature.com
Objectives: Non-alcoholic fatty liver disease (NAFLD) is an obesity-associated disease, and
in obesity adipokines are believed to be involved in the development of NAFLD. However, it …