Fucoidan-dependent increased membrane components in HepG2 cells: Effect of fucoidan is not due to gene expression

K Hayakawa, T Nagamine - Cancer Genomics & Proteomics, 2014 - cgp.iiarjournals.org
Background: The precise mechanism of the therapeutic effects of fucoidan (sulphated
polyfucose) on cultured hepatocarcinoma HepG2 cells is as yet unclear. Materials and …

[HTML][HTML] Differences in cell death and cell cycle following fucoidan treatment in high-density HT-29 colon cancer cells

IH Kim, MJ Kwon, TJ Nam - Molecular Medicine …, 2017 - spandidos-publications.com
Fucoidan, a sulfated polysaccharide present in marine brown seaweed, has been
demonstrated to inhibit in vivo and in vitro growth of cells. The present study was conducted …

Fucoidan-induced ID-1 suppression inhibits the in vitro and in vivo invasion of hepatocellular carcinoma cells

Y Cho, EJ Cho, JH Lee, SJ Yu, YJ Kim, CY Kim… - Biomedicine & …, 2016 - Elsevier
Hepatocellular carcinoma (HCC) is a fast growing tumor associated with a high tendency for
vascular invasion and distant metastasis. Recently, we reported that fucoidan displays …

[HTML][HTML] Effects of fucoidan on proliferation, AMP-activated protein kinase, and downstream metabolism-and cell cycle-associated molecules in poorly differentiated …

T Kawaguchi, M Hayakawa… - International …, 2015 - spandidos-publications.com
Survival rates are low in patients with poorly differentiated hepatocellular carcinoma (HCC).
Fucoidan, a sulfated polysaccharide derived from brown seaweed, has anticancer activity; …

[HTML][HTML] Fucoidan inhibits angiogenesis induced by multiple myeloma cells

F Liu, G Luo, Q Xiao, L Chen, X Luo… - Oncology …, 2016 - spandidos-publications.com
Multiple myeloma (MM) remains an incurable hematological neoplasms. Our previous
studies showed that Fucoidan possessed anti-myeloma effect by inducing apoptosis and …

[HTML][HTML] Antitumor effect and molecular mechanism of fucoidan in NSCLC

X Chen, L Sun, X Wei, H Lu, Y Tan, Z Sun… - … Medicine and Therapies, 2021 - Springer
Background Fucoidan, a water-soluble polysaccharide, exerts anticoagulant and antiviral
functions. It was recently reported that fucoidan also exerts an antitumor function. Lung …

Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro

S Fukahori, H Yano, J Akiba… - Molecular …, 2008 - spandidos-publications.com
Fucoidan, the general term for sulfated polysaccharides, is reported to engage in various
biological activities having anti-tumor, anti-coagulation and anti-viral effects. Though it has …

Fucoidan: Biological activity in liver diseases

J Li, C Guo, J Wu - The American journal of Chinese medicine, 2020 - World Scientific
Fucoidan is a type of polysaccharide rich in sulfuric acid groups and is mainly found in
brown algae. Due to its extensive biological activities, such as anticoagulant, antitumor …

[HTML][HTML] Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy

HY Hsu, PA Hwang - Clinical and Translational Medicine, 2019 - Springer
The chemical composition of fucoidan, a kind of sulfated polysaccharide mainly derived from
brown seaweed, includes a substantial percentage of l-fucose. Fucoidan has various …

[HTML][HTML] Anticancer effect of fucoidan on cell proliferation, cell cycle progression, genetic damage and apoptotic cell death in HepG2 cancer cells

P Arumugam, K Arunkumar, L Sivakumar, M Murugan… - Toxicology reports, 2019 - Elsevier
The centre of the attraction of this article is inevitably associated with fucoidan polymers in
terms of brown seaweed such as Turbinaria conoides. Fucoidan is a sulphated …