SOD2-and NRF2-associated gene signature to predict radioresistance in head and neck cancer

JK Noh, SR Woo, M Yun, MK Lee… - Cancer Genomics & …, 2021 - cgp.iiarjournals.org
Background: We propose a novel prognostic biomarker-based strategy for increasing the
efficacy of radiotherapy (RT) in head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses

GR You, AJ Cheng, LY Lee, YC Huang, H Liu, YJ Chen… - BMC cancer, 2019 - Springer
Background Radiotherapy is an indispensable treatment modality in head and neck cancer
(HNC), while radioresistance is the major cause of treatment failure. The aim of this study is …

Radiation-sensitive genetic prognostic model identifies individuals at risk for radiation resistance in head and neck squamous cell carcinoma

P You, S Liu, Q Li, D Xie, L Yao, C Guo, Z Guo… - Journal of Cancer …, 2023 - Springer
Background The advantages of radiotherapy for head and neck squamous cell carcinoma
(HNSCC) depend on the radiation sensitivity of the patient. Here, we established and …

RNA-Seq analysis of peripheral blood mononuclear cells reveals unique transcriptional signatures associated with radiotherapy response of nasopharyngeal …

G Liu, X Zeng, B Wu, J Zhao, Y Pan - Cancer biology & therapy, 2020 - Taylor & Francis
Radiotherapy is the main treatment for nasopharyngeal carcinoma (NPC); however,
radioresistance limits the therapeutic efficacy and prognosis of patients with NPC. Here, we …

Combining factors on protein and gene level to predict radioresponse in head and neck cancer cell lines

L Farnebo, F Jerhammar, R Ceder… - Journal of oral …, 2011 - Wiley Online Library
J Oral Pathol Med (2011) 40: 739–746 Background: Radiotherapy is the main therapy for
head and neck squamous cell carcinoma (HNSCC); however, treatment resistance and local …

[HTML][HTML] Combination of radiosensitivity gene signature and PD-L1 status predicts clinical outcome of patients with locally advanced head and neck squamous cell …

D Dai, Y Guo, Y Shui, J Li, B Jiang… - Frontiers in Molecular …, 2021 - frontiersin.org
Aim: The aim of our study was to investigate the potential predictive value of the combination
of radiosensitivity gene signature and PD-L1 expression for the prognosis of locally …

A novel seven-gene panel predicts the sensitivity and prognosis of head and neck squamous cell carcinoma treated with platinum-based radio (chemo) therapy

L Wang, Y Yang, L Feng, C Tan, H Ma, S He… - European Archives of …, 2021 - Springer
Purpose The aim of the study is to identify a reliable gene panel to predict the prognosis of
HNSCC patients by integrated genomic analysis. Methods Co-expression gene networks …

[HTML][HTML] Prediction of radiosensitivity in head and neck squamous cell carcinoma based on multiple omics data

J Liu, M Han, Z Yue, C Dong, P Wen, G Zhao… - Frontiers in …, 2020 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is a malignant tumor. Radiotherapy (RT)
is an important treatment for HNSCC, but not all patients derive survival benefit from RT due …

[HTML][HTML] A novel panel of biomarkers predicts radioresistance in patients with squamous cell carcinoma of the head and neck

J Akervall, S Nandalur, J Zhang, CN Qian… - European journal of …, 2014 - Elsevier
Purpose Global gene expression analysis was performed on pre-treatment biopsies from
patients with squamous cell carcinoma of the head and neck (SCCHN) to discover …

Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma

F Jerhammar, R Ceder, S Garvin… - Cancer biology & …, 2010 - Taylor & Francis
Radiotherapy remains the backbone of head and neck cancer therapy but response is
sometimes impeded by tumor radioresistance. Identifying predictive biomarkers of …