Transcriptomic analysis in liquid biopsy identifies circulating PCTAIRE-1 mRNA as a biomarker in NSCLC

JWC Chang, CL Shih, CL Wang, JD Luo… - Cancer Genomics & …, 2020 - cgp.iiarjournals.org
Background/Aim: Circulating mRNA can be a useful source of cancer biomarkers. We took
advantage of direct transcriptomic analysis in plasma RNA to identify novel mRNA markers …

[HTML][HTML] Clinical verification of plasma messenger RNA as novel noninvasive biomarker identified through bioinformatics analysis for lung cancer

D Zhou, W Tang, X Liu, HX An, Y Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer (LC) remains associated with significant mortality worldwide. The lack of
reliable noninvasive biomarkers and targeted therapies contributes to poor survival rate …

Tumor‐educated leukocytes mRNA as a diagnostic biomarker for non‐small cell lung cancer

L Niu, W Guo, X Song, X Song, L Xie - Thoracic cancer, 2021 - Wiley Online Library
Background This study aimed to investigate the diagnostic and prognostic role of tumor‐
educated leukocytes (TELs) mRNA in Chinese patients with non‐small cell lung cancer …

Diagnostic significance of circulating long noncoding RNA PCAT6 in patients with non-small cell lung cancer

L Wan, L Zhang, K Fan, JJ Wang - OncoTargets and therapy, 2017 - Taylor & Francis
Aim We have previously shown that the long noncoding RNA prostate cancer-associated
transcript 6 (PCAT6) promoted the proliferation and invasion of lung adenocarcinoma …

Circulating tumor DNA predicts the outcome of chemotherapy in patients with lung cancer

M Zhang, C Huang, H Zhou, D Liu, R Chen… - Thoracic …, 2022 - Wiley Online Library
Abstract Background Circulating tumor DNA (ctDNA) has potential as a specific,
noninvasive, and cost‐effective new biomarker for patients with lung cancer. This study …

Combined detection of CEA, CK-19 and c-met mRNAs in peripheral blood: a highly sensitive panel for potential molecular diagnosis of non-small cell lung cancer

CC Sheu, MY Chang, HC Chang, JR Tsai, SR Lin… - Oncology, 2006 - karger.com
Objective: Detection of tumor-related mRNA in blood has become a potential cancer
diagnostic approach. However, the sensitivity of single-marker assays is not high enough for …

Long intergenic noncoding RNA LINC00173 as a potential serum biomarker for diagnosis of non-small-cell lung cancer

Q Yang, S Kong, M Zheng, Y Hong, J Sun… - Cancer …, 2020 - content.iospress.com
BACKGROUND: Long intergenic non-coding RNA (lincRNA) belongs to a special type of
RNA that is unable to encode proteins but has been proved to play a role in gene regulation …

Importin subunit alpha‐2 is identified as a potential biomarker for non‐small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome

CI Wang, CL Wang, CW Wang… - … journal of cancer, 2011 - Wiley Online Library
The cancer cell secretome may contain potentially useful biomarkers. In this study, we
integrated the profiles of secreted proteins in lung cancer cell lines with mRNA expression …

[HTML][HTML] Application of circulating tumor DNA as a biomarker for non-small cell lung cancer

J Yang, Y Hui, Y Zhang, M Zhang, B Ji, G Tian… - Frontiers in …, 2021 - frontiersin.org
Background Non-small cell lung cancer (NSCLC) is one of the most prevalent causes of
cancer-related death worldwide. Recently, there are many important medical advancements …

[HTML][HTML] Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients

S Simonovic, C Hinze, KM Schmidt-Ott, J Busch… - BMC urology, 2020 - Springer
Background RNA sequencing data is providing abundant information about the levels of
dysregulation of genes in various tumors. These data, as well as data based on older …