NDRG1-PLAG1 and TRPS1-PLAG1 fusion genes in chondroid syringoma

I Panagopoulos, L Gorunova… - Cancer Genomics & …, 2020 - cgp.iiarjournals.org
Background/Aim: Chondroid syringoma is a rare benign tumor emanating from sweat
glands. Although rearrangements of the pleomorphic adenoma gene 1 (PLAG1) have been …

PLAG1 expression in cutaneous mixed tumors: an immunohistochemical and molecular genetic study

A Matsuyama, M Hisaoka, H Hashimoto - Virchows Archiv, 2011 - Springer
Cutaneous mixed tumors, also known as chondroid syringomas, are benign cutaneous
adnexal tumors that exhibit remarkable histopathological similarities to pleomorphic …

Fusion of the genes PHF1 and TFE3 in malignant chondroid syringoma

I Panagopoulos, L Gorunova… - Cancer Genomics & …, 2019 - cgp.iiarjournals.org
Background/Aim: Malignant chondroid syringoma is a rare tumor of unknown pathogenesis.
Materials and Methods: Genetic analyses were performed on a malignant chondroid …

Differential expression of PLAG1 in apocrine and eccrine cutaneous mixed tumors: evidence for distinct molecular pathogenesis

E Russell-Goldman, A Dubuc… - The American Journal of …, 2020 - journals.lww.com
Cutaneous mixed tumors, also known as chondroid syringomas, are benign adnexal
neoplasms that share histomorphologic features with pleomorphic adenomas of the salivary …

SMARCA2‐NR4A3 is a novel fusion gene of extraskeletal myxoid chondrosarcoma identified by RNA next‐generation sequencing

S Wei, J Pei, M von Mehren… - Genes …, 2021 - Wiley Online Library
Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain differentiation,
characterized by recurrent chromosomal translocation involving NR4A3 (9q22. 33) in more …

[HTML][HTML] Whole-Transcriptome Sequencing Identifies Novel IRF2BP2-CDX1 Fusion Gene Brought about by Translocation t(1;5)(q42;q32) in Mesenchymal …

KB Nyquist, I Panagopoulos, J Thorsen, L Haugom… - PloS one, 2012 - journals.plos.org
Mesenchymal chondrosarcomas (MCs) account for 3–10% of primary chondrosarcomas.
The cytogenetic literature includes only ten such tumours with karyotypic information and no …

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative …

JF Shern, L Chen, J Chmielecki, JS Wei, R Patidar… - Cancer discovery, 2014 - AACR
Despite gains in survival, outcomes for patients with metastatic or recurrent
rhabdomyosarcoma remain dismal. In a collaboration between the National Cancer Institute …

Glandular differentiation in dedifferentiated chondrosarcoma: molecular evidence of a rare phenomenon

G Jour, Y Liu, R Ricciotti, C Pritchard, BL Hoch - Human Pathology, 2015 - Elsevier
Epithelial glandular differentiation in dedifferentiated chondrosarcoma has not been
described. Our patient was a 64-year-old man with a history of prostate cancer status post …

[HTML][HTML] A genetic model for central chondrosarcoma evolution correlates with patient outcome

W Cross, I Lyskjær, T Lesluyes, S Hargreaves… - Genome medicine, 2022 - Springer
Background Central conventional chondrosarcoma (CS) is the most common subtype of
primary malignant bone tumour in adults. Treatment options are usually limited to surgery …

Extraskeletal myxoid chondrosarcoma of the vulva with PLAG1 gene activation: Molecular genetic characterization of 2 cases

S Dotlic, Z Gatalica, W Wen, A Ghazalpour… - Applied …, 2014 - journals.lww.com
Extraskeletal myxoid chondrosarcoma (EMC) is a rare mesenchymal neoplasm, rarely
reported in the genitourinary tract with only 5 cases reported in the vulva. We investigated 2 …