S100A4, a member of the S100 family of proteins involved in calcium signalling, has come
into the fore in recent years on account of its close relationship with tumour development …

The fatality of cancer is mainly bestowed to the property of otherwise benign tumor cells to
become malignant and invade surrounding tissues by circumventing normal tissue barriers …

The growth, invasion and metastatic spread of cancer have been identified with the
deregulation of cell proliferation, altered intercellular and cell-substratum adhesion and …

Multiple reports have focused on S100A4's role in cancer progression, specifically its ability
to enhance metastasis. However, recent studies have linked S100A4 to several diseases …

Metastasis is the leading cause of cancer-related death and directly associates with cancer
progression, resistance to anticancer therapy, and poor patient survival. Current efforts …

The role of S100A4 in tumor progression and metastasis is well documented in numerous
research articles and summarized in several reviews [1-3]. Currently S100A4 is categorized …

Tumor cell invasion and metastasis are complex multi-step cellular processes that involve
the ability of malignant cells to escape the primary tumor, migrate to distant sites within the …

S100A4 (also known as Mts1, metastasin, p9Ka, pEL98, CAPL, calvasculin, Fsp-1, placental
calcium-binding protein) belongs to the family of EF-hand calcium-binding proteins, whose …

S100A16 is a member of the S100 protein family. S100A16 is expressed in a variety of
human tissues, although at varying levels. S100A16 expression is especially high in tissues …

Cancer growth and progression are characterised by the deregulation of cell proliferation,
motility and intercellular and cell-substratum adhesion. This leads to the acquisition …