Circulating messenger RNA profiling with microarray and next-generation sequencing: cross-platform comparison
CL Shih, JD Luo, JWC Chang, TL Chen… - Cancer Genomics & …, 2015 - cgp.iiarjournals.org
Background: Circulating mRNA is a less invasive and more easily accessed source of
samples for biomedical research and clinical applications. However, it is of poor quality. We …
samples for biomedical research and clinical applications. However, it is of poor quality. We …
Direct screening of plasma circulating microRNAs
P Songia, M Chiesa, V Valerio, D Moschetta… - RNA biology, 2018 - Taylor & Francis
Circulating microRNAs (miRNAs) are considered as reliable candidates for biomarker
discovery. RNA-Sequencing has become the most suitable technique to accurately quantify …
discovery. RNA-Sequencing has become the most suitable technique to accurately quantify …
[HTML][HTML] Profiling the circulating mRNA transcriptome in human liver disease
The human circulation contains cell-free DNA and non-coding microRNA (miRNA). Less is
known about the presence of messenger RNA (mRNA). This report profiles the human …
known about the presence of messenger RNA (mRNA). This report profiles the human …
[HTML][HTML] Clinical verification of plasma messenger RNA as novel noninvasive biomarker identified through bioinformatics analysis for lung cancer
D Zhou, W Tang, X Liu, HX An, Y Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer (LC) remains associated with significant mortality worldwide. The lack of
reliable noninvasive biomarkers and targeted therapies contributes to poor survival rate …
reliable noninvasive biomarkers and targeted therapies contributes to poor survival rate …
[HTML][HTML] Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood
J Kim, Z Xu, PA Marignani - NPJ Genomic Medicine, 2021 - nature.com
Lung cancer accounts for more than half of the new cancers diagnosed world-wide with poor
survival rates. Despite the development of chemical, radiological, and immunotherapies …
survival rates. Despite the development of chemical, radiological, and immunotherapies …
[HTML][HTML] A Cross-Comparison of High-Throughput Platforms for Circulating MicroRNA Quantification, Agreement in Risk Classification, and Biomarker Discovery in …
C Gargiuli, L De Cecco, A Mariancini, MF Iannò… - Frontiers in …, 2022 - frontiersin.org
Background Circulating microRNAs (ct-miRs) are promising cancer biomarkers. This study
focuses on platform comparison to assess performance variability, agreement in the …
focuses on platform comparison to assess performance variability, agreement in the …
Transcriptomics today: Microarrays, RNA-seq, and more
C Tachibana - Science, 2015 - science.org
Gene expression analysis has become routine, thanks to microarrays and now RNA
sequencing, which is helping researchers discover novel RNA forms and variants. New …
sequencing, which is helping researchers discover novel RNA forms and variants. New …
Dynamic and static circulating cancer microRNA biomarkers–a validation study
For cancers and other pathologies, early diagnosis remains the most promising path to
survival. Profiling of longitudinal cohorts facilitates insights into trajectories of biomarkers …
survival. Profiling of longitudinal cohorts facilitates insights into trajectories of biomarkers …
Plasma RNA sequencing of extracellular RNAs reveals potential biomarkers for non-small cell lung cancer
L Wang, J Wang, E Jia, Z Liu, Q Ge, X Zhao - Clinical Biochemistry, 2020 - Elsevier
Background Lung cancer is one of the most common malignancies, and it has extremely
high incidence and mortality rates. Although there have been many studies focused on lung …
high incidence and mortality rates. Although there have been many studies focused on lung …
The circulating transcriptome as a source of non‐invasive cancer biomarkers: concepts and controversies of non‐coding and coding RNA in body fluids
M Fernandez‐Mercado, L Manterola… - Journal of cellular …, 2015 - Wiley Online Library
The gold standard for cancer diagnosis remains the histological examination of affected
tissue, obtained either by surgical excision, or radiologically guided biopsy. Such …
tissue, obtained either by surgical excision, or radiologically guided biopsy. Such …