Blood is the most common source of biomarkers for use in the diagnosis and prognosis of
malignant disease. Utilizing proteomic technology for biomarker identification offers greatly …

BACKGROUND There is an urgent need for blood-based molecular tests to assist in the
detection and diagnosis of cancers at an early stage, when curative interventions are still …

In recent years, many advances have been made in the field of proteomics. The use of high-
throughput methods for analyzing complex proteomes, in particular SELDI mass …

Proteome analysis promises to be valuable for the identification of tissue and serum
biomarkers associated with human malignancies. In addition, proteome technologies offer …

The rapid development of proteomics technology in the past decades has led to further
human understanding of tumor research, and in some ways, the technology plays a very …

Although discovering proteomic biomarker by using mass spectrometry technique is
promising, its rate of introducing proteomic biomarker approved by the US Food and Drug …

Probably no topic has generated more excitement in the world of proteomics than the search
for biomarkers. This excitement has been generated by two realities: the constant need for …

It is sometimes difficult to believe that it was only 4 years ago that John Yates published his
work using multidimensional chromatography combined with electrospray ionization mass …

Simple Summary The traditional approach in identifying cancer related protein biomarkers
has focused on evaluation of a single peptide/protein in tissue or circulation. At best, this …

A cancer biomarker is a molecular signature that indicates the physiologic and pathologic
changes in a particular tissue or cell type during cancer development. When such molecular …