Proteomic analysis of differently archived breast cancer tissues
AC Bougnoux, A Mange… - Cancer Genomics & …, 2012 - cgp.iiarjournals.org
Currently, the most common practice of human breast tissue preservation is formalin fixation
which ensures good quality for histopathological analyses but damages DNA, RNA, and …
which ensures good quality for histopathological analyses but damages DNA, RNA, and …
[HTML][HTML] Proteomic developments in the analysis of formalin-fixed tissue
OJR Gustafsson, G Arentz, P Hoffmann - Biochimica et Biophysica Acta …, 2015 - Elsevier
Retrospective proteomic studies, including those which aim to elucidate the molecular
mechanisms driving cancer, require the assembly and characterization of substantial patient …
mechanisms driving cancer, require the assembly and characterization of substantial patient …
[HTML][HTML] Preservation of biomolecules in breast cancer tissue by a formalin-free histology system
Background The potential problems associated with the use of formalin in histology, such as
health hazards, degradation of RNA and cross-linking of proteins are well recognized. We …
health hazards, degradation of RNA and cross-linking of proteins are well recognized. We …
[HTML][HTML] Proteomics on fixed tissue specimens—a review
BA Reimel, S Pan, DH May, SA Shaffer… - Current …, 2009 - ncbi.nlm.nih.gov
The vast majority of clinical tissue samples are formalin-fixed and paraffin-preserved. This
type of preservation has been considered an obstacle to protein extraction from these …
type of preservation has been considered an obstacle to protein extraction from these …
Guided protein extraction from formalin‐fixed tissues for quantitative multiplex analysis avoids detrimental effects of histological stains
KF Becker, C Schott, I Becker… - PROTEOMICS–Clinical …, 2008 - Wiley Online Library
Formalin fixed and paraffin embedded (FFPE) tissues are the basis for histopathological
diagnosis of many diseases around the world. For translational research and routine …
diagnosis of many diseases around the world. For translational research and routine …
Setting proteins free: progresses and achievements in proteomics of formalin‐fixed, paraffin‐embedded tissues
Formalin fixation, followed by paraffin embedding, is long established as the standard
procedure for the stabilization and preservation of tissue architecture, essential for enabling …
procedure for the stabilization and preservation of tissue architecture, essential for enabling …
A novel procedure for protein extraction from formalin‐fixed paraffin‐embedded tissues
T Rodríguez‐Rigueiro, M Valladares‐Ayerbes… - …, 2011 - Wiley Online Library
Most of the archived pathological specimens in hospitals are kept as formalin‐fixed paraffin‐
embedded tissues (FFPE) for long‐term preservation. Up to now, these samples are only …
embedded tissues (FFPE) for long‐term preservation. Up to now, these samples are only …
Proteomic analysis of PAXgene-fixed tissues
B Ergin, S Meding, R Langer, M Kap… - Journal of proteome …, 2010 - ACS Publications
Formalin fixation and paraffin embedding is the standard technique for preserving biological
material for both storage and histological analysis. Although recent progress has been made …
material for both storage and histological analysis. Although recent progress has been made …
Efficient method for the proteomic analysis of fixed and embedded tissues
DE Palmer-Toy, B Krastins, DA Sarracino… - Journal of proteome …, 2005 - ACS Publications
Formalin-fixed and paraffin-embedded (FFPE) tissues present a particular challenge for
proteomic analysis. Yet, most of the archived tissues in hospitals and tissue banks …
proteomic analysis. Yet, most of the archived tissues in hospitals and tissue banks …
[HTML][HTML] Successful protein extraction from over-fixed and long-term stored formalin-fixed tissues
C Wolff, C Schott, P Porschewski, B Reischauer… - PLoS …, 2011 - journals.plos.org
One of the major breakthroughs in molecular pathology during the last decade was the
successful extraction of full-length proteins from formalin-fixed and paraffin-embedded …
successful extraction of full-length proteins from formalin-fixed and paraffin-embedded …