One of the important strategies for the treatment of cancer is gene therapy which has the
potential to exclusively eradicate malignant cells, without any damage to the normal tissues …

Cell-based gene therapy holds a great promise for the treatment of human malignancy.
Among different cells, mesenchymal stem cells (MSCs) are emerging as valuable anti …

Biodegradable polymeric nanoparticles have the potential to be safer alternatives to viruses
for gene delivery; however, their use has been limited by poor efficacy in vivo. In this work …

The rising risk of lung cancer has become a primary global concern with high mortality and
mobility. Presently, clinically used anticancer drugs show limited efficacy and significant side …

A growing area of research is focused on cancer therapy, and new therapeutic approaches
are welcomed. Mesenchymal stem cell (MSC)-based gene therapy is a promising strategy in …

Malignant glioma, which is characterized by diffuse infiltration into the normal brain
parenchyma, is the most aggressive primary brain tumor with dismal prognosis. Over the …

Personalized medicine is a new approach toward safer and even cheaper treatments with
minimal side effects and toxicity. Planning a therapy based on individual properties causes …

Gliomas are a dismal disease associated with poor survival and high morbidity. Current
standard treatments have reached a therapeutic plateau even after combining maximal safe …

Mesenchymal stromal cells (MSC) can be exploited as cellular delivery vehicles for the
enzymes converting non-toxic prodrugs to toxic substances. Because of their inherent …

Glioblastoma is the most aggressive brain tumor characterized by diffuse infiltration into the
normal brain parenchyma. Neural stem cells are known to possess the tumor-tropic …