Diagnostic and prognostic epigenetic biomarkers in cancer
Growing cancer incidence and mortality worldwide demands development of accurate
biomarkers to perfect detection, diagnosis, prognostication and monitoring. Urologic …
biomarkers to perfect detection, diagnosis, prognostication and monitoring. Urologic …
[HTML][HTML] Differential expression patterns of Eph receptors and ephrin ligands in human cancers
CTJ Kou, RP Kandpal - BioMed Research International, 2018 - hindawi.com
Eph receptors constitute the largest family of receptor tyrosine kinases, which are activated
by ephrin ligands that either are anchored to the membrane or contain a transmembrane …
by ephrin ligands that either are anchored to the membrane or contain a transmembrane …
[HTML][HTML] Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome
DM Brantley-Sieders, A Jiang, K Sarma… - PloS one, 2011 - journals.plos.org
Pre-clinical studies provide compelling evidence that Eph family receptor tyrosine kinases
(RTKs) and ligands promote cancer growth, neovascularization, invasion, and metastasis …
(RTKs) and ligands promote cancer growth, neovascularization, invasion, and metastasis …
[HTML][HTML] Quantitative analysis of cell-free DNA in ovarian cancer
X Shao, Y He, M Ji, X Chen, J Qi, W Shi… - Oncology …, 2015 - spandidos-publications.com
The aim of the present study was to investigate the association between cell-free DNA (cf-
DNA) levels and clinicopathological characteristics of patients with ovarian cancer using a …
DNA) levels and clinicopathological characteristics of patients with ovarian cancer using a …
[HTML][HTML] DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression
JE Wu, YY Wu, CH Tung, YT Tsai, HY Chen… - Theranostics, 2020 - ncbi.nlm.nih.gov
The loss of cancer-cell junctions and escape from the primary-tumor microenvironment are
hallmarks of metastasis. A tight-junction protein, Claudin 1 (CLDN1), is a metastasis …
hallmarks of metastasis. A tight-junction protein, Claudin 1 (CLDN1), is a metastasis …
Dancing with the dead: Eph receptors and their kinase-null partners
L Truitt, A Freywald - Biochemistry and Cell Biology, 2011 - cdnsciencepub.com
Eph receptor tyrosine kinases and their ligands, ephrins, are membrane proteins
coordinating a wide range of biological functions both in developing embryos and in adult …
coordinating a wide range of biological functions both in developing embryos and in adult …
Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes
GC Harburg, L Hinck - Journal of mammary gland biology and neoplasia, 2011 - Springer
Abstract Slit, Netrin, Ephrin, and Semaphorin's roles in development have expanded greatly
in the past decade from their original characterization as axon guidance molecules (AGMs) …
in the past decade from their original characterization as axon guidance molecules (AGMs) …
[HTML][HTML] Identification of potentially critical differentially methylated genes in nasopharyngeal carcinoma: A comprehensive analysis of methylation profiling and gene …
L Hui, J Zhang, X Ding, X Guo… - Oncology …, 2017 - spandidos-publications.com
The present study aimed to identify potentially critical differentially methylated genes
associated with the progression of nasopharyngeal carcinoma (NPC). Methylation profiling …
associated with the progression of nasopharyngeal carcinoma (NPC). Methylation profiling …
Tyrosine kinase-deficient EphB6 receptor-dependent alterations in proteomic profiles of invasive breast carcinoma cells as determined by difference gel …
RP Kandpal - Cancer Genomics & Proteomics, 2010 - cgp.iiarjournals.org
The expression profiles of the erythropoietin producing hepatocellular carcinoma (Eph)
receptor family of tyrosine kinases have been previously shown to provide molecular …
receptor family of tyrosine kinases have been previously shown to provide molecular …
Inhibitors targeting epigenetic modifications in cancer
Epigenetics is an extraordinary mechanism by which our body controls genomic destiny
without altering the underlying nucleotide sequence. Various epigenetic modifiers such as …
without altering the underlying nucleotide sequence. Various epigenetic modifiers such as …