[HTML][HTML] Mass spectrometry-based label-free quantitative proteomics

W Zhu, JW Smith, CM Huang - BioMed research international, 2010 - hindawi.com
In order to study the differential protein expression in complex biological samples, strategies
for rapid, highly reproducible and accurate quantification are necessary. Isotope labeling …

Proteomics of colorectal cancer: overview of discovery studies and identification of commonly identified cancer-associated proteins and candidate CRC serum …

CR Jimenez, JC Knol, GA Meijer, RJA Fijneman - Journal of proteomics, 2010 - Elsevier
Colorectal cancer (CRC) is a common cause of cancer-related mortality in the developed
world. Improved methods for early detection and disease management are urgently needed …

Up-regulation of type I collagen during tumorigenesis of colorectal cancer revealed by quantitative proteomic analysis

X Zou, B Feng, T Dong, G Yan, B Tan, H Shen… - Journal of …, 2013 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. The discovery of
non-invasive biomarker candidates for diagnosis and prognosis is important for the …

[HTML][HTML] Discovery and pharmacological evaluation of STEAP4 as a novel target for HER2 overexpressing breast cancer

IM Orfanou, O Argyros, A Papapetropoulos… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BC) is a highly heterogeneous disease encompassing multiple subtypes with
different molecular and histopathological features, disease prognosis, and therapeutic …

Mass spectrometry of peptides and proteins from human blood

P Zhu, P Bowden, D Zhang… - Mass spectrometry …, 2011 - Wiley Online Library
It is difficult to convey the accelerating rate and growing importance of mass spectrometry
applications to human blood proteins and peptides. Mass spectrometry can rapidly detect …

Label-free mass spectrometry-based proteomics for biomarker discovery and validation

TV Pham, SR Piersma, G Oudgenoeg… - Expert review of …, 2012 - Taylor & Francis
For most diseases, better biomarkers are urgently needed to enable (early) detection,
diagnosis, prognosis, stratification for therapy and response monitoring. Proteomics …

Evolution of clinical proteomics and its role in medicine

E Boja, T Hiltke, R Rivers, C Kinsinger… - Journal of Proteome …, 2011 - ACS Publications
Significant progress has been made in characterizing and sequencing genomic alterations
of biospecimens from several types of cancer. Understanding the functional changes in the …

[HTML][HTML] Applying mass spectrometry based proteomic technology to advance the understanding of multiple myeloma

J Micallef, M Dharsee, J Chen, S Ackloo… - Journal of hematology & …, 2010 - Springer
Multiple myeloma (MM) is the second most common hematological malignancy in adults. It is
characterized by clonal proliferation of terminally differentiated B lymphocytes and over …

Quantitative mass spectrometry for colorectal cancer proteomics

J Martínez‐Aguilar, J Chik, J Nicholson… - PROTEOMICS …, 2013 - Wiley Online Library
This review documents the uses of quantitative MS applied to colorectal cancer (CRC)
proteomics for biomarker discovery and molecular pathway profiling. Investigators are …

In silico analysis validates proteomic findings of formalin-fixed paraffin embedded cutaneous squamous cell carcinoma tissue

A Azimi, KL Kaufman, M Ali, S Kossard… - Cancer genomics & …, 2016 - cgp.iiarjournals.org
Background: Cutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer
but there are no comprehensive proteomic studies on this entity. Materials and Methods: We …