Despite the remarkable enhancements in breast cancer classification and characterization,
an exhaustive comprehension of the underlying carcinogenic processes and an accurate …

Proteomic approaches are continuing to make headways in cancer research by helping to
elucidate complex signaling networks that underlie tumorigenesis and disease progression …

Kinases play a prominent role in tumor development, pointing to the presence of specific
phosphorylation patterns in tumor tissues. Here, we investigate whether recently developed …

Mutations of genes in tumor cells of Triple Negative subset of Breast Cancer (TNBC)
deregulate pathways of signal transduction. The loss of tumor suppressor gene PTEN is the …

Purpose: Identification of a generic response biomarker by comparison of
chemotherapeutics with different action mechanisms on several noninvasive biomarkers in …

Comparative microarray analyses provided insight into understanding transcript changes
during cancer progression; however, a reproducible signature underlying breast …

Breast cancer is the most common cancer among women. It is estimated that 7% of women
who have breast cancer will develop a subsequent second independent breast tumor within …

Reflecting the interdisciplinary nature of biotechnology, this book covers the role of targeted
delivery of polymeric nanodrugs to cancer cells, microbial detoxifying enzymes in …

Over 9,000 women with breast cancer are enrolled annually on clinical trials sponsored by
the National Cancer Institute (NCI), accounting for about one-third of all patients enrolled on …

Introduction: Cancer is one of the leading causes of morbidity and mortality worldwide. A
hallmark of cancer is evasion of apoptosis leading to tumor progression and drug resistance …