[HTML][HTML] Collagen remodeling along cancer progression providing a novel opportunity for cancer diagnosis and treatment

K Song, Z Yu, X Zu, G Li, Z Hu, Y Xue - International Journal of Molecular …, 2022 - mdpi.com
The extracellular matrix (ECM) is a significant factor in cancer progression. Collagens, as the
main component of the ECM, are greatly remodeled alongside cancer development. More …

New target DDR1: A “double-edged sword” in solid tumors

Y Tian, F Bai, D Zhang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Globally, cancer is a major catastrophic disease that seriously threatens human health.
Thus, there is an urgent need to find new strategies to treat cancer. Among them, identifying …

CircFoxo3 promotes adriamycin resistance through regulation of miR-199a-5p/ATP binding cassette subfamily C member 1 Axis in hepatocellular carcinoma

W Huang, F Huang, C Feng - OncoTargets and therapy, 2020 - Taylor & Francis
Introduction Chemotherapy resistance is the main cause of poor prognosis in patients with
hepatocellular carcinoma (HCC). Therefore, it is important to understand the molecular …

[HTML][HTML] The yin and yang of discoidin domain receptors (DDRs): implications in tumor growth and metastasis development

S Majo, P Auguste - Cancers, 2021 - mdpi.com
The tumor microenvironment is a complex structure composed of the extracellular matrix
(ECM) and nontumoral cells (notably cancer-associated fibroblasts (CAFs) and immune …

The role of miR-199b-3p in regulating Nrf2 pathway by dihydromyricetin to alleviate septic acute kidney injury

X Tian, Y Liu, H Wang, J Zhang, L Xie, Y Huo… - Free Radical …, 2021 - Taylor & Francis
The pathophysiology of septic acute kidney injury (AKI) is very complex and the fatality is
high. Nrf2 is crucial for septic AKI, and dihydromyricetin (DMY) has a protective effect on LPS …

[HTML][HTML] MicroRNA Expression Signatures in Clear Cell Renal Cell Carcinoma: High-Throughput Searching for Key miRNA Markers in Patients from the Volga-Ural …

I Gilyazova, E Ivanova, A Izmailov… - International Journal of …, 2023 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is characterized by high molecular genetic
heterogeneity, metastatic activity and unfavorable prognosis. MicroRNAs (miRNA) are 22 …

[HTML][HTML] Rolling circle amplification (RCA)-based biosensor system for the fluorescent detection of miR-129-2-3p miRNA

Y Ye, Y Lin, Z Chi, J Zhang, F Cai, Y Zhu, D Tang, Q Lin - PeerJ, 2022 - peerj.com
Herein, a versatile fluorescent bioanalysis platform for sensitive and specific screening of
target miRNA (miR-129-2-3p) was innovatively designed by applying target-induced rolling …

High expression of microRNA-199a-5p is associated with superior clinical outcomes in patients with locally advanced rectal cancer

DW Baek, G Kim, BW Kang, HJ Kim, SY Park… - Journal of Cancer …, 2020 - Springer
Purpose We aimed to identify biomarkers of response to preoperative CRT in patients with
LARC using comprehensive miRNA analysis. Methods This study included 65 rectal cancer …

A Three-microRNA panel in serum: serving as a potential diagnostic biomarker for renal cell carcinoma

G Huang, X Li, Z Chen, J Wang, C Zhang… - Pathology & Oncology …, 2020 - Springer
Purpose Renal cell carcinoma (RCC) accounts for about 120,000 death each year. Although
surgery is a routine treatment, RCC could be fatal if not diagnosed at an early stage. This …

LncRNA CDKN2B‐AS1 contributes to glioma development by regulating the miR‐199a‐5p/DDR1 axis

J Lu, Y Chen, L Wen, Q Zhou… - The Journal of Gene …, 2022 - Wiley Online Library
Background Although cyclin‐dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B‐
AS1) is upregulated in glioma, its function and potential mechanism in glioma remain …