Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …

Artemisinin is an extract from the plant Artemisia annua. With its semi-synthetic derivatives,
they form a group of well-known and efficacious antimalarial drugs. Recent studies have …

In recent years, the functions of glial cells, namely, astrocytes and microglia, have gained
prominence in several diseases of the central nervous system, especially in glioblastoma …

Glioblastoma (GBM) is the most common and malignant astrocytic glioma, accounting for
about 90% of all brain tumors with poor prognosis. Despite recent advances in …

The canonical Wnt/β-catenin pathway is up-regulated in gliomas and involved in
proliferation, invasion, apoptosis, vasculogenesis and angiogenesis. Nuclear β-catenin …

The WNT (Wingless/Integrated) signaling pathway is implicated in various stages of
glioblastoma, which is an aggressive brain tumor for which therapeutic options are limited …

Wnt is a complex signaling pathway involved in the regulation of crucial biological functions
such as development, proliferation, differentiation and migration of cells, mainly stem cells …

Glioma is one of the most treatment‐refractory intracranial tumors, and the aberrant
expressed Wnt/β‐catenin pathway is closely associated with glioma malignancy. In this …

Glioblastoma (GB) is the most lethal brain tumor, and Wingless (Wg)-related integration site
(WNT) pathway activation in these tumors is associated with a poor prognosis. Clinically, the …

The Hippo signaling pathway is highly conserved from Drosophila melanogaster to
mammals and plays a crucial role in organ size control, tissue regeneration, and tumor …