S100 proteins in cancer
AR Bresnick, DJ Weber, DB Zimmer - Nature Reviews Cancer, 2015 - nature.com
In humans, the S100 protein family is composed of 21 members that exhibit a high degree of
structural similarity, but are not functionally interchangeable. This family of proteins …
structural similarity, but are not functionally interchangeable. This family of proteins …
[HTML][HTML] New angiogenic regulators produced by TAMs: perspective for targeting tumor angiogenesis
I Larionova, E Kazakova, T Gerashchenko… - Cancers, 2021 - mdpi.com
Simple Summary Since the targeting of a single pro-angiogenic factor fails to improve
oncological disease outcome, significant efforts have been made to identify new pro …
oncological disease outcome, significant efforts have been made to identify new pro …
Significance of p53 overexpression in the prediction of the malignant transformation risk of oral potentially malignant disorders: A systematic review and meta-analysis
P Ramos-Garcia, MA Gonzalez-Moles… - Oral oncology, 2022 - Elsevier
Objectives To evaluate the current evidence in relation to the predictive value of p53
overexpression as a biomarker of the malignant transformation risk in oral potentially …
overexpression as a biomarker of the malignant transformation risk in oral potentially …
The NOTCH Pathway in Head and Neck Squamous Cell Carcinoma
T Fukusumi, JA Califano - Journal of dental research, 2018 - journals.sagepub.com
Comprehensive genomic analyses have been performed for head and neck squamous cell
carcinoma (HNSCC), revealing a significant rate of NOTCH1 mutations and identifying …
carcinoma (HNSCC), revealing a significant rate of NOTCH1 mutations and identifying …
“Omics” in oral cancer: New approaches for biomarker discovery
Objectives In this review paper, we explored the application of “omics” approaches in the
study of oral cancer (OC). It will provide a better understanding of how “omics” approaches …
study of oral cancer (OC). It will provide a better understanding of how “omics” approaches …
Targeting Notch4 in cancer: molecular mechanisms and therapeutic perspectives
M Xiu, X Zeng, R Shan, W Wen, J Li… - Cancer Management and …, 2021 - Taylor & Francis
The dysregulation of Notch signaling is found in many cancers and is closely related to
cancer progression. As an important Notch receptor, abnormal Notch4 expression affects …
cancer progression. As an important Notch receptor, abnormal Notch4 expression affects …
Calcium role in human carcinogenesis: a comprehensive analysis and critical review of literature
B Kadio, S Yaya, A Basak, K Djè, J Gomes… - Cancer and Metastasis …, 2016 - Springer
The central role played by calcium ion in biological systems has generated an interest for its
potential implication in human malignancies. Thus, lines of research, on possible …
potential implication in human malignancies. Thus, lines of research, on possible …
[HTML][HTML] S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma
Background Altered expression of S100A16 has been reported in human cancers, but its
biological role in tumorigenesis is not fully understood. This study aimed to investigate the …
biological role in tumorigenesis is not fully understood. This study aimed to investigate the …
[HTML][HTML] miR-203 inhibits arecoline-induced epithelial‑mesenchymal transition by regulating secreted frizzled-related protein 4 and transmembrane-4 L six family …
L Zheng, X Jian, F Guo, N Li, C Jiang… - Oncology …, 2015 - spandidos-publications.com
Oral submucous fibrosis (OSF) is a potentially malignant disease predominantly found in
Asian people. The areca nut has been implicated in this disease. Arecoline, one of the areca …
Asian people. The areca nut has been implicated in this disease. Arecoline, one of the areca …
Signature of genetic associations in oral cancer
Oral cancer etiology is complex and controlled by multi-factorial events including genetic
events. Candidate gene studies, genome-wide association studies, and next-generation …
events. Candidate gene studies, genome-wide association studies, and next-generation …