Overexpression of transmembrane protein 2 (TMEM2), a novel hyaluronidase, predicts poor prognosis in pancreatic ductal adenocarcinoma

Y Kudo, N Sato, Y Adachi, T Amaike, A Koga, S Kohi… - Pancreatology, 2020 - Elsevier
Background Abnormal metabolism of hyaluronan (HA), a major component of extracellular
matrix, is a hallmark of cancer. Our previous studies have shown the importance of enzymes …

[HTML][HTML] Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer

T Oba, N Sato, Y Adachi, T Amaike, Y Kudo, A Koga… - Scientific reports, 2021 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is characterised by dense desmoplasia and
hypoxic microenvironment. Our previous reports demonstrated that hyaluronan (HA), especially …

[HTML][HTML] Hyaluronan activated-metabolism phenotype (HAMP) in pancreatic ductal adenocarcinoma

Y Kudo, S Kohi, K Hirata, M Goggins, N Sato - Oncotarget, 2019 - ncbi.nlm.nih.gov
Background: The aggressiveness of pancreatic ductal adenocarcinoma (PDAC) is enhanced
by its interactions with stromal extracellular matrix, notably with hyaluronan (HA). Our …

Concurrent Overexpression of Two Hyaluronidases, KIAA1199 and TMEM2, Strongly Predicts Shorter Survival After Resection in Pancreatic Ductal Adenocarcinoma

Y Kudo, N Sato, T Oba, Y Adachi, T Amaike, A Koga… - Pancreas, 2022 - journals.lww.com
Objectives Pancreatic ductal adenocarcinoma (PDAC) is characterized by accelerated
hyaluronan metabolism. Our previous studies have shown increased expression of 2 newly …

[HTML][HTML] Triple bypass for advanced pancreatic head cancer associated with biliary stricture, duodenal stenosis, and recurrent obstructive pancreatitis

Y Kudo, N Sato, T Tamura, K Hirata - Surgical Case Reports, 2016 - Springer
Bypass surgery for cancer of the pancreatic head is usually done to palliate the obstructive
symptoms in the biliary and/or digestive system. However, it is uncommon for patients to …

[HTML][HTML] Prognostic and functional role of hyaluronan‑binding protein 1 in pancreatic ductal adenocarcinoma

…, N Sato, T Oba, T Amaike, Y Kudo… - Oncology …, 2022 - spandidos-publications.com
Hyaluronan‑binding protein 1 (HABP1) is among the molecules known to bind to hyaluronan
and is involved in a variety of cellular processes, including cell proliferation and migration. …

Preoperative factors predicting the need for additional ports during single‐incision laparoscopic cholecystectomy

N Sato, K Yabuki, Y Kudo, A Koga… - Asian Journal of …, 2016 - Wiley Online Library
Introduction Single‐incision laparoscopic cholecystectomy (SILC) is gaining popularity as a
minimally invasive technique that provides some benefits in terms of improved cosmesis. …

Receptor for Hyaluronic Acid-mediated Motility (RHAMM) Is Associated With Prostate Cancer Migration and Poor Prognosis

A Minato, Y Kudo, H Noguchi, S Kohi… - Cancer Genomics & …, 2023 - cgp.iiarjournals.org
Background/Aim: Hyaluronic acid (HA) is a large glycosaminoglycan composed of an
extracellular matrix. The HA-rich microenvironment and receptors of HA have been suggested to …

Prognostic and Functional Role of Hyaluronan-binding Protein 1 (HABP1) in Pancreatic Ductal Adenocarcinoma

Y Adachi, T Oba, T Amaike, Y Kudo, S Kohi… - 2020 - researchsquare.com
Background: Hyaluronan-binding protein 1 (HABP1) is one of molecules that binds to
hyaluronan and is involved in a variety of cellular processes including cell proliferation and …

[CITATION][C] Patients with lung recurrence after curative resection for pancreatic ductal adenocarcinoma have a better prognosis than those with recurrence at other …

Y Watanabe, K Nishihara, Y Niina, Y Kudo, K Kurata… - J Pancreas, 2017