Background Since the introduction of laparoscopic colectomy, improved short-term surgical
results have been noted in the literature. Therefore, efforts have shifted to reducing the …

Dysfunctional mitochondria have been shown to enhance cancer cell proliferation, reduce
apoptosis, and increase chemoresistance. Chemoresistance develops in nearly all patients …

In recent years, natural orifice specimen extraction surgery (NOSES) in the treatment of
colorectal cancer has attracted widespread attention. The potential benefits of NOSES including …

Objectives The appendix may modulate colon microbiota and bowel inflammation. We
investigated whether appendectomy alters colorectal cancer risk. Methods We identified a cohort …

BACKGROUND: Double and triple stapling techniques to close the rectal stump in laparoscopic
anterior resection are fraught with technical drawbacks that could possibly be avoided …

Anastomotic leaks (ALs) are associated with increased perioperative morbidity and mortality,
prolonged length of stay, higher readmission rates, the potential need for further operative …

Background Although reduced port laparoscopic surgery (RPLS), defined as laparoscopic
surgery performed with the minimum possible number of ports and/or small-sized ports, is less …

Background MicroRNAs regulate gene expression at the posttranscriptional level and play
important roles in tumor development, progression, and metastasis. The aim of this study was …

TGFβ contributes to chemoresistance in advanced colorectal cancer (CRC) via diverse
immune-microenvironment mechanisms. Here, we found that cancer cell autonomous TGFβ …

Aim The purpose of the present study was to conduct a systematic review and meta-analysis
of the published literature to assess the diagnostic performance of FDG-PET or PET/CT in …