User profiles for STEVEN G. CLARKE
Steven G. ClarkeProfessor of Chemistry and Biochemistry, UCLA Verified email at mbi.ucla.edu Cited by 48961 |
[PDF][PDF] Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
…, J Chung, RSB Clark, PGH Clarke, SG Clarke… - Autophagy, 2008 - Taylor & Francis
Research in autophagy continues to accelerate, 1 and as a result many new scientists are
entering the field. Accordingly, it is important to establish a standard set of criteria for …
entering the field. Accordingly, it is important to establish a standard set of criteria for …
[HTML][HTML] Protein arginine methylation in mammals: who, what, and why
MT Bedford, SG Clarke - Molecular cell, 2009 - cell.com
The covalent marking of proteins by methyl group addition to arginine residues can promote
their recognition by binding partners or can modulate their biological activity. A small family …
their recognition by binding partners or can modulate their biological activity. A small family …
[HTML][HTML] Uncovering the human methyltransferasome
TC Petrossian, SG Clarke - Molecular & Cellular Proteomics, 2011 - ASBMB
… Clarke SG … Clarke SG … Clarke CF …
[HTML][HTML] Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues
…, T Sandberg, R Kelly, SG Clarke - Journal of Biological …, 2012 - ASBMB
Full-length human protein arginine methyltransferase 7 (PRMT7) expressed as a fusion protein
in Escherichia coli was initially found to generate only ω-N G -monomethylated arginine …
in Escherichia coli was initially found to generate only ω-N G -monomethylated arginine …
L-Ascorbate biosynthesis in higher plants: the role of VTC2
CL Linster, SG Clarke - Trends in plant science, 2008 - cell.com
In the past year, the last missing enzyme of the l-galactose pathway, the linear form of which
appears to represent the major biosynthetic route to l-ascorbate (vitamin C) in higher plants, …
appears to represent the major biosynthetic route to l-ascorbate (vitamin C) in higher plants, …
[PDF][PDF] 2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling
We discovered recently that the central metabolite α-ketoglutarate (α-KG) extends the
lifespan of C. elegans through inhibition of ATP synthase and TOR signaling. Here we find, …
lifespan of C. elegans through inhibition of ATP synthase and TOR signaling. Here we find, …
[HTML][HTML] PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145
The human genome encodes a family of nine protein arginine methyltransferases (PRMT1–9),
whose members can catalyse three distinct types of methylation on arginine residues. …
whose members can catalyse three distinct types of methylation on arginine residues. …
[HTML][HTML] Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs
Arginine methylation is a common posttranslational modification that is found on both histone
and non-histone proteins. Three types of arginine methylation exist in mammalian cells: …
and non-histone proteins. Three types of arginine methylation exist in mammalian cells: …
Protein methylation at the surface and buried deep: thinking outside the histone box
SG Clarke - Trends in biochemical sciences, 2013 - cell.com
Methylated lysine and arginine residues in histones represent a crucial part of the histone
code, and recognition of these methylated residues by protein interaction domains modulates …
code, and recognition of these methylated residues by protein interaction domains modulates …
[HTML][HTML] Arabidopsis VTC2 Encodes a GDP-l-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants*♦
The first committed step in the biosynthesis of l-ascorbate from d-glucose in plants requires
conversion of GDP-l-galactose to l-galactose 1-phosphate by a previously unidentified …
conversion of GDP-l-galactose to l-galactose 1-phosphate by a previously unidentified …