The development of nontoxic natural agents with chemopreventive activity against colon
cancer is the focus of investigation in many laboratories. Curcumin (feruylmethane), a natural …

Colorectal cancer is the third most common cause of cancer-related death in both men and
women in the western hemisphere. According to the American Cancer Society, an estimated …

In addition to the direct effect of estrogen on mitochondria and the redox cycling of catechol
estrogen, estrogen-induced proinflammatory cytokines, such as interleukin-1 beta (IL-1β) …

A possible role of insulinlike growth factor I (IGF-I) and IGF-I receptors in the proliferation of
human colon cancer has, to the best of the authors' knowledge, not been examined as yet. To …

The purpose of this study was to examine the mechanism (s) and differential cell-killing
effects of Anvirzel TM, an extract of oleander (Nerium oleander; family-Apocynaceae), and its …

Named as the guardian of the genome, p53 is a tumor suppressor that regulates cell function,
often through many different mechanisms such as DNA repair, apoptosis, cell cycle arrest, …

Cyclin-dependent kinases (CDKs) have been considered promising drug targets for a
number of years, but most CDK inhibitors have failed rigorous clinical testing. Recent studies …

Sweet potato ( Ipomoea batatas ) leaves or greens, extensively consumed as a vegetable in
Africa and Asia, are an excellent source of dietary polyphenols such as anthocyanins and …

Background: Neonatal sepsis is one of the most common causes of neonatal mortality in the
developing world. This study aims to determine the incidence, the bacteriological profile of …

… The work summarized in this manuscript was supported in part by the grants awarded to
Satya Narayan from the National Cancer Institute, NIH (CA77721); the 2001-Research …