A new antiinflammatory agent identified as 8-[C-β-d-[2-O-(E)-cinnamoyl]glucopyranosyl]-2-[(R)-2-hydroxypropyl]-7-methoxy-5-methylchromone
(1) has been isolated from Aloe …

Background: Lung cancer (LC) is the leading cause of deaths caused by cancer worldwide.
A diagnostic test for LC is needed for monitoring high-risk populations. Patients and Methods…

The structure of the plasma membrane affects its function. Changes in membrane fluidity
with concomitant effects on membrane protein activities and cellular communication often …

Background/Aim: Insulin resistance (IR) is linked to increased risk of cardiovascular disease
and cancer. We examined safety and efficacy of the natural product diethyl azelate (DEA) in …

Background/Aim: Alterations of plasma membrane fluidity are characteristic of many diseases
but the intentional modulation of membrane fluidity with drugs has been less studied. We …

Hepsulfam (NSC 329680, 1,7-heptanediol disulfamate) is an alkylating agent that showed
excellent activity against mouse and human mammary carcinoma in preclinical studies. We …

We have determined that hepsulfam, in common with its structural homologue busulfan,
alkylates both free guanosine and GMP in DNA at the 7 nitrogen. Mass spectral analysis of the …

Caesium-133 NMR measurements were used to study the complexation of rubidium and
caesium cations by 13 different crown ethers in acetonitrile. The 133 Cs chemical shift data …

Insulin resistance (IR), accompanied by an impaired cellular glucose uptake, characterizes
diverse pathologies that include, but are not limited to, metabolic disease, prediabetes and …

Background/Aim: Mycobacterium ulcerans causes the necrotizing skin disease Buruli ulcer (BU),
characterized by the formation of subcutaneous lesions and immunosuppression …