The improvement of diagnostic techniques and the efficacy of new therapies in clinical practice
have allowed cancer patients to reach a higher chance to be cured together with a better …

Matrix metalloproteases (MMPs) are a family of well-known enzymes which operate prevalently
in the extracellular domain, where they fulfil the function of remodeling the extracellular …

Background Attempts to reduce morbidity and mortality in breast cancer is based on efforts
to identify novel biomarkers to support prognosis and therapeutic choices. The present study …

Background: The Human Epidermal Growth Factor Receptor 2 (HER-2), overexpressed in
25-30% of breast carcinomas (BC), is the therapeutic target for trastuzumab, a recombinant …

Thyroid carcinomas account for a minority of all malignant tumours but, after those of the
gonads, they represent the most common forms of endocrine cancers. They include several …

Background/Aim: Radiation therapy (RT) represents a therapeutic option in breast cancer (BC).
Even if a great number of BC patients receive RT, not all of them report benefits, due to …

Purpose The present study reports for the first time a large‐scale proteomic screening of the
occurrence, subcellular localization and relative quantification of the S 100 A 7 protein …

The present investigation has been conducted on one hundred tissue fragments of breast
cancer, collected and immediately cryopreserved following the surgical resection. The …

Background In regenerative medicine the maintenance of stem cell properties is of crucial
importance. Ageing is considered a cause of reduced stemness capability. The limbus is a …

The breast cancer (BC) disease is characterized by a wide heterogeneity at both clinical and
molecular level, showing distinct subtypes with different clinical outcomes. Thus, the choice …