Persistent infection with a high‐risk human papillomavirus (hrHPV) is generally accepted as
a necessary cause of cervical cancer. However, cervical cancer is a rare complication of an …

Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

With the trend of moving molecular tests from clinical laboratories to on-site testing, there is
a need for nucleic acid based diagnostic tools combining the sensitivity, specificity and …

Background A substantial number of microRNAs (miRNAs) is subject to epigenetic silencing
in cancer. Although epigenetic silencing of tumour suppressor genes is an important feature …

The natural history of cancers associated with virus exposure is intriguing, since only a minority
of human tissues infected with these viruses inevitably progress to cancer. However, the …

Background: Cervical carcinogenesis is initiated by infection with high-risk (ie, carcinogenic)
human papillomavirus (HPV) types. The subsequent progression from premalignant …

Infection with high-risk human papillomavirus (HR-HPV) has been associated with intraepithelial
neoplasia and carcinomas at various sites of the anogenital tract, including the cervix, …

Hemidesmosomes (HDs) are stable anchoring structures that mediate the link between the
intermediate filament cytoskeleton and the cell substratum. We investigated the contribution …

Background Cytology is a widely used method of triaging women who test positive for human
papillomavirus (HPV). However, self-sampled specimens, which can substantially increase …

Cervical cancer results from persistent infection with high‐risk human papillomavirus (hrHPV).
Common genetic aberrations in cervical (pre)cancers encompass large genomic regions …