Tissue- and cell-specific deletion of the Aqp4 gene is required to differentiate between the
numerous pools of aquaporin-4 (AQP4) water channels. A glial-conditional Aqp4 knockout …

Expression of the water channel aquaporin‐4 (AQP4) at the blood–brain interface is dependent
upon the dystrophin associated protein complex. Here we investigated whether deletion …

Astrocytic endfeet cover the brain surface and form a sheath around the cerebral vasculature.
An emerging concept is that endfeet control blood–brain water transport and drainage of …

Key roles of macroglia are inextricably coupled to specialized membrane domains. The
perivascular endfoot membrane has drawn particular attention, as this domain contains a unique …

Background/Aim: Hoffa’s disease is anterior knee pain presumably stemming from
inflammatory fibrous hyperplasia of the infrapatellar fat pad (Hoffa’s pad). The etiology and …

Background/Aim: Fusion of histone-lysine N-methyltransferase 2A gene (KMT2A) with the
Rho guanine nucleotide exchange factor 12 gene (ARHGEF12), both located in 11q23, was …

The outcome of pediatric B-cell precursor acute lym-phoblastic leukemia (BCP ALL) has
improved tremendously in the last decades, from being an invariably fatal disease until the …

Background/Aim: Previous reports have associated the KMT2A-ELL fusion gene, generated
by t(11;19)(q23;p13.1), with acute myeloid leukemia (AML). We herein report a KMT2A-ELL …

Aquaporin-4 (AQP4) water channels are concentrated in astrocytic endfoot membranes at
the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms underpinning the …

The glymphatic system transports cerebrospinal fluid (CSF) into the brain via arterial perivascular
spaces and removes interstitial fluid from the brain along perivenous spaces and white …