The nuclear pore complex protein Nup88 is overexpressed in tumor cells. Immunohistochemical
studies have shown that this overexpression is linked to higher aggressiveness of …

Background Mammaglobin (h-MAM) is expressed mainly by breast epithelial cells, and this
feature has been used to detect circulating breast cancer cells and occult metastases in …

Background: Bcl-2 is one of the most important antiapoptotic genes. Although it facilitates
the survival of tumor cells, its expression has been consistently associated with a better …

Background: Both VEGF and CD105 (endoglin) have been identified as markers of tumor
angiogenesis and prognosis in breast cancer. They have always been studied in this kind of …

Background The balance between the expression of the antiapoptotic gene Bcl-2 and the
proapoptotic gene Bax is considered a good indicator of the apoptotic activity of tumor cells. Bcl…

Background: Breast cancer grows in a hormone-rich environment which influences its
biological features and thus, ultimately, its clinical behavior. Circulating hormone levels were …

Nup88 is a nuclear pore complex protein which is overexpressed in a variety of human tumors
of the stomach, colon, liver, pancreas, breast, lung, ovary, uterus, prostate and kidney. A …

Background: A gene located on the q11.23 region of the male chromosome, RBMY, which
plays a role in spermatogenesis, is down-regulated in testicular cancer. RBMY is a diverged …

Background. In the case of DNA-aneuploid tumors there are no clear guidelines as to which
S-phase fraction is the more relevant one: that corresponding to either the diploid or the …