T H -17 cells are a distinct lineage of proinflammatory T helper cells that are essential for
autoimmune disease. In mice, commitment to the T H -17 lineage is dependent on transforming …

Background—Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor
of nitric oxide (NO) synthase. Because endothelial NO elaboration is impaired in …

Aberrant cytokine expression has been proposed as an underlying cause of psoriasis, although
it is unclear which cytokines play critical roles. Interleukin (IL)-23 is expressed in human …

Objectives: To evaluate the efficacy and safety of 18 months of tafamidis treatment in patients
with early-stage V30M transthyretin familial amyloid polyneuropathy (TTR-FAP). Methods: …

This study aims to understand how website interactivity (active control and reciprocal
communication) can impact purchase intention through website involvement and how the impacts …

Classroom exams can assess students' knowledge of only a subset of the material taught in
a course. What are the implications of this approach for long-term retention? Three …

Objective To estimate the prevalence, types, and sociodemographic and biobehavioral
correlates of antinuclear antibodies (ANAs) in the US. Methods We conducted a cross‐sectional …

Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …

PURPOSE Reducing radiation treatment dose could improve the quality of life (QOL) of
patients with good-risk human papillomavirus–associated oropharyngeal squamous cell …

The turn of the 21st century had witnessed a surge of interest in the centrosome and its causal
relation to human cancer development-a postulate that has existed for almost a century. …