User profiles for J.E. GARCÍA-ORTIZ
José Elías García-OrtizCentro de Investigación Biomédica de Occidente, CMNO, IMSS Verified email at imss.gob.mx Cited by 2446 |
SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome
…, B Brasseur, C Cesaretti, JE García-Ortiz… - Nature …, 2017 - nature.com
Arhinia, or absence of the nose, is a rare malformation of unknown etiology that is often
accompanied by ocular and reproductive defects. Sequencing of 40 people with arhinia revealed …
accompanied by ocular and reproductive defects. Sequencing of 40 people with arhinia revealed …
Foxl2 is required for commitment to ovary differentiation
C Ottolenghi, S Omari, JE Garcia-Ortiz… - Human molecular …, 2005 - academic.oup.com
Genetic control of female sex differentiation from a bipotential gonad in mammals is poorly
understood. We find that mouse XX gonads lacking the forkhead transcription factor Foxl2 …
understood. We find that mouse XX gonads lacking the forkhead transcription factor Foxl2 …
[HTML][HTML] Foxl2functions in sex determination and histogenesis throughout mouse ovary development
JE Garcia-Ortiz, E Pelosi, S Omari, T Nedorezov… - BMC developmental …, 2009 - Springer
Background Partial loss of function of the transcription factor FOXL2 leads to premature
ovarian failure in women. In animal models, Foxl2 is required for maintenance, and possibly …
ovarian failure in women. In animal models, Foxl2 is required for maintenance, and possibly …
[HTML][HTML] JHelioviewer-Time-dependent 3D visualisation of solar and heliospheric data
…, P Jiggens, JP García-Ortiz, J Ireland… - Astronomy & …, 2017 - aanda.org
Context. Solar observatories are providing the world-wide community with a wealth of data,
covering wide time ranges (eg Solar and Heliospheric Observatory, SOHO), multiple …
covering wide time ranges (eg Solar and Heliospheric Observatory, SOHO), multiple …
Dynamics of the ovarian reserve and impact of genetic and epidemiological factors on age of menopause
…, E Simonsick, A Forabosco, JE Garcia-Ortiz… - Biology of …, 2015 - academic.oup.com
The narrow standard age range of menopause, ∼50 yr, belies the complex balance of
forces that govern the underlying formation and progressive loss of ovarian follicles (the “ovarian …
forces that govern the underlying formation and progressive loss of ovarian follicles (the “ovarian …
[HTML][HTML] Paternal determinants in preeclampsia
…, M Sosa-Macias, E Teran, JE Garcia-Ortiz… - Frontiers in …, 2019 - frontiersin.org
Preeclampsia is a condition associated with high rates of maternal-fetal morbidity and mortality.
It usually occurs in 3–10% of nulliparous women and 18% of previously affected women. …
It usually occurs in 3–10% of nulliparous women and 18% of previously affected women. …
Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia–anophthalmia–coloboma (MAC) spectrum cases
…, JL Tovilla-Canales, JE Garcia-Ortiz… - British journal of …, 2010 - bjo.bmj.com
Background/aims Microphthalmia-anophthalmia-coloboma (MAC) are congenital eye
malformations causing a significant percentage of visually impairments in children. Although these …
malformations causing a significant percentage of visually impairments in children. Although these …
High‐resolution molecular characterization of the HLA class I and class II in the Tarahumara Amerindian population
JE García‐Ortiz, L Sandoval‐Ramírez… - Tissue …, 2006 - Wiley Online Library
We describe for the first time the high‐resolution profiling of HLA‐A, ‐B, ‐C, ‐DRB1, ‐DQB1
and ‐DPB1 in a culturally and geographically distinct Mexican ethnic group, the Tarahumaras…
and ‐DPB1 in a culturally and geographically distinct Mexican ethnic group, the Tarahumaras…
A missense mutation, p. V132G, in the X‐linked spermine synthase gene (SMS) causes Snyder–Robinson syndrome
…, J Sanchez‐Corona, JE Garcia‐Ortiz - American Journal of …, 2009 - Wiley Online Library
Snyder–Robinson syndrome (SRS, OMIM 309583) is a rare X‐linked syndrome characterized
by mental retardation, marfanoid habitus, skeletal defects, osteoporosis, and facial …
by mental retardation, marfanoid habitus, skeletal defects, osteoporosis, and facial …
[HTML][HTML] Toward a Comprehensive Framework for Ensuring Security and Privacy in Artificial Intelligence
W Villegas-Ch, J García-Ortiz - Electronics, 2023 - mdpi.com
The rapid expansion of artificial intelligence poses significant challenges in terms of data
security and privacy. This article proposes a comprehensive approach to develop a framework …
security and privacy. This article proposes a comprehensive approach to develop a framework …