Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease
M Iyo, H Namba, K Fukushi, H Shinotoh, S Nagatsuka… - The Lancet, 1997 - thelancet.com
Background Acetylcholinesterase activity, a marker for degeneration of the central cholinergic
system, has consistently been reported, in necropsy brain studies, to be reduced in the …
system, has consistently been reported, in necropsy brain studies, to be reduced in the …
Positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in Parkinson's disease and …
H Shinotoh, H Namba, M Yamaguchi… - Annals of …, 1999 - Wiley Online Library
We measured brain acetylcholinesterase activity in 16 patients with Parkinson's disease (PD),
12 patients with progressive supranuclear palsy (PSP), and 13 age‐matched controls, …
12 patients with progressive supranuclear palsy (PSP), and 13 age‐matched controls, …
Positive Correlations Between Cerebral Protein Synthesis Rates and Deep Sleep in Macaca mulatta
…, K Mori, M Ito, S Suda, H Namba… - European Journal of …, 1997 - Wiley Online Library
Local rates of cerebral protein synthesis (ICPS leu ), were determined with the autoradiographic
L‐[1‐ 14 C]leucine method in seven awake and seven asleep, adult rhesus monkeys …
L‐[1‐ 14 C]leucine method in seven awake and seven asleep, adult rhesus monkeys …
Progressive loss of cortical acetylcholinesterase activity in association with cognitive decline in Alzheimer's disease: a positron emission tomography study
H Shinotoh, H Namba, K Fukushi… - Annals of Neurology …, 2000 - Wiley Online Library
We measured brain acetylcholinesterase activity in 30 patients with Alzheimer's disease (AD)
and 14 age‐matched controls by positron emission tomography (PET) and using a carbon …
and 14 age‐matched controls by positron emission tomography (PET) and using a carbon …
[HTML][HTML] The Global DNA Methylation Surrogate LINE-1 Methylation Is Correlated with MGMT Promoter Methylation and Is a Better Prognostic Factor for Glioma
Gliomas are the most frequently occurring primary brain tumor in the central nervous system
of adults. Glioblastoma multiformes (GBMs, WHO grade 4) have a dismal prognosis despite …
of adults. Glioblastoma multiformes (GBMs, WHO grade 4) have a dismal prognosis despite …
Comparison of hemodynamics of intracranial aneurysms between MR fluid dynamics using 3D cine phase-contrast MRI and MR-based computational fluid dynamics
Introduction Hemodynamics is thought to play a very important role in the initiation, growth,
and rupture of intracranial aneurysms. The purpose of our study was to compare …
and rupture of intracranial aneurysms. The purpose of our study was to compare …
Benefits of interferon‐β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study
BACKGROUND: The aim of the current study was to catalog genomic and epigenomic
abnormalities in newly diagnosed glioblastoma patients and determine the correlation among …
abnormalities in newly diagnosed glioblastoma patients and determine the correlation among …
Human behavioral assessments in current research of Parkinson's disease
…, Y Yang, F Hua, G Ding, G Wen, H Namba… - Neuroscience & …, 2016 - Elsevier
Parkinson’s disease (PD) is traditionally classified as a movement disorder because patients
mainly complain about motor symptoms. Recently, non-motor symptoms of PD have been …
mainly complain about motor symptoms. Recently, non-motor symptoms of PD have been …
Bystander effect-mediated gene therapy of gliomas using genetically engineered neural stem cells
…, J Yamamoto, M Koide, N Yokota, H Namba - Cancer gene …, 2005 - nature.com
Since neural stem cells (NSCs) have the ability to migrate toward a tumor mass, genetically
engineered NSCs were used for the treatment of gliomas. We first evaluated the “bystander …
engineered NSCs were used for the treatment of gliomas. We first evaluated the “bystander …
Cdc6 expression as a marker of proliferative activity in brain tumors
…, N Yokota, S Nishizawa, H Namba - Oncology …, 2001 - spandidos-publications.com
Antibodies against human proteins that regulate DNA replication such as Cdc6 and Mcm5
became available as a new marker of proliferation. We performed immunohistochemical …
became available as a new marker of proliferation. We performed immunohistochemical …