Safe adoptive transfer of virus‐specific T‐cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation

…, C Peters, FR Schuster, R Beck… - British journal of …, 2006 - Wiley Online Library
During periods of immunosuppression, such as postallogeneic stem cell transplantation (SCT),
patients are at significant risk for severe viral infections. Human adenovirus (HAdV) …

Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem …

…, WA Bethge, MS Topp, FR Schuster… - Blood, The Journal …, 2010 - ashpublications.org
Cytomegalovirus (CMV) disease and infection refractory to antiviral treatment after allogeneic
stem cell transplantation (allo-SCT) is associated with a high mortality. Adoptive transfer of …

Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT

…, H Einsele, PG Schlegel, FR Schuster… - Blood, The Journal …, 2015 - ashpublications.org
Hematopoietic stem cell transplantation (HSCT) has improved over the last few decades.
However, viral infections are often refractory to pharmacologic treatment and require alternative …

Lowest numbers of primary CD8+ T cells can reconstitute protective immunity upon adoptive immunotherapy

…, GU Grigoleit, FR Schuster… - Blood, The Journal …, 2014 - ashpublications.org
Patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) are
threatened by potentially lethal viral manifestations like cytomegalovirus (CMV) reactivation. …

[HTML][HTML] Anti-GD2 antibody dinutuximab beta and low-dose interleukin 2 after haploidentical stem-cell transplantation in patients with relapsed neuroblastoma: a …

…, W Schwinger, R Meisel, FR Schuster… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
PURPOSE Patients with relapsed high-risk neuroblastoma (rHR-NB) have a poor prognosis.
We hypothesized that graft-versus-neuroblastoma effects could be elicited by …

Treatment with caspofungin in immunocompromised paediatric patients: a multicentre survey

AH Groll, A Attarbaschi, FR Schuster… - Journal of …, 2006 - academic.oup.com
Objectives: Although a paediatric dosage has not been established, caspofungin is occasionally
used in paediatric patients. We conducted a multicentre retrospective survey to obtain …

Immunotherapy with the trifunctional anti‐CD 20 x anti‐CD 3 antibody FBTA 05 (Lymphomun) in paediatric high‐risk patients with recurrent CD 20‐positive B cell …

FR Schuster, M Stanglmaier… - British Journal of …, 2015 - Wiley Online Library
Children with B cell malignancies refractory to standard therapy are known to have a poor
prognosis and very limited treatment options. Here, we report on the treatment and follow‐up …

Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL

…, H Pichler, N Scherenschlich, FR Schuster… - Bone marrow …, 2019 - nature.com
Although allogeneic hematopoietic stem-cell transplantation (HSCT) provides high cure rates
for children with high-risk acute lymphoblastic leukaemia (ALL), relapses remain the main …

[HTML][HTML] Next-generation-sequencing-spectratyping reveals public T-cell receptor repertoires in pediatric very severe aplastic anemia and identifies a β chain CDR3 …

…, T Keller, S Weber, M Gombert, FR Schuster… - …, 2013 - ncbi.nlm.nih.gov
Current diagnostic approaches that characterize T-cell deficiency by analyzing diversity of T-cell
receptor sequences effectuate limited informational gain about the actual restrictiveness…

[HTML][HTML] Reduction of minimal residual disease in pediatric B-lineage acute lymphoblastic leukemia by an Fc-optimized CD19 antibody

…, S Aulwurm, E Pyz, FR Schuster, R Meisel… - Molecular Therapy, 2016 - cell.com
Prognosis of primary refractory and relapsed pediatric B-lineage acute lymphoblastic leukemia
(ALL) is very poor. Relapse rates significantly correlate with persistent minimal residual …