[HTML][HTML] Analysis of hereditary cancer syndromes by using a panel of genes: novel and multiple pathogenic mutations
…, I Xanthakis, G Xepapadakis, E Banu, DT Eniu… - BMC cancer, 2019 - Springer
Background Hereditary cancer predisposition syndromes are responsible for approximately
5–10% of all diagnosed cancer cases. In the past, single-gene analysis of specific high risk …
5–10% of all diagnosed cancer cases. In the past, single-gene analysis of specific high risk …
[HTML][HTML] Lipidomic Signatures for Colorectal Cancer Diagnosis and Progression Using UPLC-QTOF-ESI+MS
Metabolomics coupled with bioinformatics may identify relevant biomolecules such as putative
biomarkers of specific metabolic pathways related to colorectal diagnosis, classification …
biomarkers of specific metabolic pathways related to colorectal diagnosis, classification …
Copy Number Variations (CNVs) account for 10.8% of pathogenic variants in patients referred for hereditary cancer testing
…, S Tansan, K Kaban, T Ozatli, DT Eniu… - Cancer genomics & …, 2023 - cgp.iiarjournals.org
Background/Aim: Germline copy number variation (CNV) is a type of genetic variant that
predisposes significantly to inherited cancers. Today, next-generation sequencing (NGS) …
predisposes significantly to inherited cancers. Today, next-generation sequencing (NGS) …
The decrease of some serum free amino acids can predict breast cancer diagnosis and progression
DT Eniu, F Romanciuc, C Moraru… - … journal of clinical and …, 2019 - Taylor & Francis
This study was targeted on a metabolomic approach to compare the blood serum free amino
acid profiles and concentration of confirmed breast cancer (stages I–III) patients to healthy …
acid profiles and concentration of confirmed breast cancer (stages I–III) patients to healthy …
Clinical utility of functional RNA analysis for the reclassification of splicing gene variants in hereditary cancer
Background: Classification of splicing variants (SVs) in genes associated with hereditary
cancer is often challenging. The aim of this study was to investigate the occurrence of SVs in …
cancer is often challenging. The aim of this study was to investigate the occurrence of SVs in …
[HTML][HTML] Prevalence of deleterious mutations among patients with breast cancer referred for multigene panel testing in a Romanian population
IG Goidescu, G Caracostea, DT Eniu… - Clujul Medical, 2018 - ncbi.nlm.nih.gov
… IULIAN GABRIEL GOIDESCU, 1, 2, * GABRIELA CARACOSTEA, 1, * DAN TUDOR ENIU,
corresponding author 3 and FLORIN VASILE STAMATIAN 1 … Goidescu I, Eniu DT …
corresponding author 3 and FLORIN VASILE STAMATIAN 1 … Goidescu I, Eniu DT …
Revisiting the implications of positive germline testing results using multi-gene panels in Breast cancer patients
Background/Aim: The use of multi-gene panels for germline testing in breast cancer enables
the estimation of cancer risk and guides risk-reducing management options. The aim of this …
the estimation of cancer risk and guides risk-reducing management options. The aim of this …
[HTML][HTML] Prevalence of MMTV-like sequences in breast cancer samples in Romanian patients-there is a geographic difference compared to the Western world
Background Breast cancer, although the most frequently diagnosed malignant tumor in
humans, has a less clear etiology compared to other frequent cancer types. Mouse-mammary …
humans, has a less clear etiology compared to other frequent cancer types. Mouse-mammary …
The role of imaging techniques in the diagnosis, staging and choice of therapeutic conduct in pregnancy associated breast cancer
…, G Nemeti, G Caracostea, DT Eniu… - Medical …, 2019 - medultrason.ro
Breast cancer diagnosed during pregnancy is at increasing incidence due to the increased
frequency of obesity, the postponement of the first pregnancy to later decades of life and the …
frequency of obesity, the postponement of the first pregnancy to later decades of life and the …
[HTML][HTML] Spectrum of High-Risk Mutations among Breast Cancer Patients Referred for Multigene Panel Testing in a Romanian Population
Simple Summary Multigene panel testing for Hereditary Breast and Ovarian Cancer using next
generation sequencing is the new standard for the identification of individuals with cancer …
generation sequencing is the new standard for the identification of individuals with cancer …