Background: The incidence of prostate cancer (PCa) has increased in recent years due to
the aging of the population and increased testing; however, mortality rates have remained …

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

The widespread use of the PSA test has led to increased detection of the disease at earlier
stages and a reduction in the number of patients where metastatic disease is found at …

Despite advances in molecular medicine, genomics, proteomics and translational research,
prostate cancer remains the second most common cause of cancer-related mortality for men …

Cellular proteomics is becoming a widespread clinical application, matching the definition
of bench-to-bedside translation. Among various fields of investigation, this approach can be …

While most chimeric antigen receptor (CAR) T-cell clinical trials are using CAR T-cell products
that target one specific antigen on multiple myeloma (MM) cells, other investigators are …

Objective We studied evolving antithrombotic therapy patterns in patients with newly diagnosed
non-valvular atrial fibrillation (AF) and ≥1 additional stroke risk factor between 2010 and …

This new volume of Methods in Enzymology continues the legacy of this premier serial with
quality chapters authored by leaders in the field. This volume covers research methods …

… Editorial support was provided by Claire Aukim-Hastie, Emily Chu, Rae Hobbs, and Jane
Tricker (TRI). SAS programming support was provided by Jagan Allu (TRI). … L …

Second, the metabolic changes linked to malignant transformation should not be
considered as a general property shared by all types of cancer. It has indeed been clearly …