Vitamin D signalling pathways in cancer: potential for anticancer therapeutics

KK Deeb, DL Trump, CS Johnson - Nature reviews cancer, 2007 - nature.com
Epidemiological studies indicate that vitamin D insufficiency could have an aetiological role
in various human cancers. Preclinical research indicates that the active metabolite of vitamin …

[HTML][HTML] Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species

…, D Xiao, Y Zeng, SC Watkins, CS Johnson… - Journal of Biological …, 2005 - ASBMB
We have shown previously that sulforaphane (SFN), a constituent of many edible cruciferous
vegetables including broccoli, suppresses growth of prostate cancer cells in culture as well …

Vitamin D: considerations in the continued development as an agent for cancer prevention and therapy

DL Trump, KK Deeb, CS Johnson - The Cancer Journal, 2010 - journals.lww.com
Considerable preclinical and epidemiologic data suggest that vitamin D may play a role in
the pathogenesis, progression, and therapy for cancer. Numerous epidemiologic studies …

Epidemiology, clinical features, and disease severity in patients with coronavirus disease 2019 (COVID-19) in a children's hospital in New York City, New York

P Zachariah, CL Johnson, KC Halabi, D Ahn… - JAMA …, 2020 - jamanetwork.com
Importance Descriptions of the coronavirus disease 2019 (COVID-19) experience in pediatrics
will help inform clinical practices and infection prevention and control for pediatric facilities…

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

…, MJ Higgins, CB Ambrosone, CS Johnson… - …, 2012 - academic.oup.com
The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density
microarray for quantifying the methylation level of over 450 000 CpG sites within human …

The role of vitamin D in cancer prevention and treatment

…, DL Trump, CS Johnson… - Rheumatic Disease …, 2012 - rheumatic.theclinics.com
Calcitriol (1, 25-dihydroxyvitamin D3), the biologically most active form of vitamin D, maintains
calcium homeostasis through its actions in intestine, bone, kidneys, and the parathyroid …

Expression and mutational analysis of MET in human solid cancers

…, AC MacKinnon, N Ramnath, C Johnson… - Genes …, 2008 - Wiley Online Library
MET receptor tyrosine kinase and its ligand hepatocyte growth factor (HGF) regulate a variety
of cellular functions, many of which can be dysregulated in human cancers. Activated MET …

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G 2 /M arrest and inducing …

…, KL Lew, Y Zeng, P Hershberger, CS Johnson… - …, 2003 - academic.oup.com
Dietary isothiocyanates (ITCs) are highly effective in affording protection against chemically
induced cancers in laboratory animals. In the present study, we demonstrate that allyl …

Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated …

D Xiao, S Choi, DE Johnson, VG Vogel, CS Johnson… - Oncogene, 2004 - nature.com
Garlic-derived organosulfides (OSCs) including diallyl trisulfide (DATS) are highly effective
in affording protection against chemically induced cancer in animals. Evidence is also …

Role of Vitamin D Receptor in the Antiproliferative Effects of Calcitriol in Tumor-Derived Endothelial Cells and Tumor Angiogenesis In vivo

…, BM Gillard, W Yu, BA Foster, DL Trump, CS Johnson - Cancer research, 2009 - AACR
Calcitriol (1,25-dihydroxycholecalciferol), the major active form of vitamin D, is antiproliferative
in tumor cells and tumor-derived endothelial cells (TDEC). These actions of calcitriol are …