User profiles for BRUCE E. TAILLON

Bruce Taillon

Codagenix
Verified email at codagenix.com
Cited by 4977

Paired-end mapping reveals extensive structural variation in the human genome

…, PM Kim, D Palejev, NJ Carriero, L Du, BE Taillon… - Science, 2007 - science.org
Structural variation of the genome involves kilobase- to megabase-sized deletions, duplications,
insertions, inversions, and complex combinations of rearrangements. We introduce high…

STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H (+)-ATPase subunit Vph1p.

MF Manolson, B Wu, D Proteau, BE Taillon… - Journal of Biological …, 1994 - ASBMB
The Saccharomyces cerevisiae gene, VPH1 (Vacuolar pH 1), encodes a 95-kDa integral
membrane subunit of the vacuolar-type H(+)-ATPase (V-ATPase) that is required for enzyme …

Transcriptome sequencing of malignant pleural mesothelioma tumors

…, LR Chirieac, ML Hartman, BE Taillon… - Proceedings of the …, 2008 - National Acad Sciences
Cancers arise by the gradual accumulation of mutations in multiple genes. We now use
shotgun pyrosequencing to characterize RNA mutations and expression levels unique to …

Analysis of TSC cortical tubers by deep sequencing of TSC1, TSC2 and KRAS demonstrates that small second‐hit mutations in these genes are rare events

…, HV Vinters, GW Mathern, DN Franz, BE Taillon… - Brain …, 2010 - Wiley Online Library
Tuberous sclerosis complex (TSC) is an often severe neurocutaneous syndrome. Cortical
tubers are the predominant neuropathological finding in TSC, and their number and location …

regA, a Volvox gene that plays a central role in germ-soma differentiation, encodes a novel regulatory protein

…, K Stark, SM Miller, W Müller, BE Taillon… - …, 1999 - journals.biologists.com
Volvox has two cell types: mortal somatic cells and immortal germ cells. Here we describe
the transposontagging, cloning and characterization of regA, which plays a central role as a …

Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing

J Archer, MS Braverman, BE Taillon, B Desany… - Aids, 2009 - journals.lww.com
Objective: Identification of low-frequency variants is of clinical importance in the identification
of preexisting drug resistance. Using ‘ultra-deep’sequencing, we address the detection of …

Mutational analysis of centrin: an EF-hand protein associated with three distinct contractile fibers in the basal body apparatus of Chlamydomonas.

BE Taillon, SA Adler, JP Suhan, JW Jarvik - The Journal of cell biology, 1992 - rupress.org
Centrin, a 20-kD phosphoprotein with four calcium-binding EF-hands, is present in the
centrosome/basal body apparatus of the green alga Chlamydomonas reinhardtii in three distinct …

Ultra deep sequencing detects a low rate of mosaic mutations in tuberous sclerosis complex

W Qin, P Kozlowski, BE Taillon, P Bouffard, AJ Holmes… - Human genetics, 2010 - Springer
Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome
caused by mutations in TSC1 and TSC2. However, 10–15% TSC patients have no mutation …

[HTML][HTML] The evolutionary analysis of emerging low frequency HIV-1 CXCR4 using variants through time—an ultra-deep approach

J Archer, A Rambaut, BE Taillon… - PLoS computational …, 2010 - journals.plos.org
Large-scale parallel pyrosequencing produces unprecedented quantities of sequence data.
However, when generated from viral populations current mapping software is inadequate …

[HTML][HTML] Second generation sequencing of the mesothelioma tumor genome

…, A Anwar, G Maulik, LR Chirieac, KF Ho, BE Taillon… - PloS one, 2010 - journals.plos.org
The current paradigm for elucidating the molecular etiology of cancers relies on the interrogation
of small numbers of genes, which limits the scope of investigation. Emerging second-…