Abstract
Molecular cloning of the transforming gene from a chemically transformed human osteosarcoma-derived cell line enables the gene to be mapped to chromosome 7 (7p11.4-7qter) and by this criterion and by direct hybridization to be shown to be unrelated to known oncogenes.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Base Sequence
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Cell Line
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Cell Transformation, Neoplastic*
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Cells, Cultured
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Chromosome Mapping
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Chromosomes, Human, 6-12 and X
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Cloning, Molecular*
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Humans
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Hybrid Cells / physiology
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Mice
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Mice, Inbred Strains
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Nucleic Acid Hybridization
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Oncogenes*
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Osteosarcoma / genetics*