IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age

Acta Neuropathol. 2016 Jul;132(1):153-5. doi: 10.1007/s00401-016-1579-4. Epub 2016 May 9.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Astrocytoma / diagnostic imaging
  • Astrocytoma / genetics*
  • Astrocytoma / pathology
  • Astrocytoma / therapy
  • Biomarkers, Tumor / genetics
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / genetics*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / therapy
  • Child
  • Fatal Outcome
  • Female
  • Glioblastoma / diagnostic imaging
  • Glioblastoma / genetics*
  • Glioblastoma / pathology
  • Glioblastoma / therapy
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Male
  • Mutation*

Substances

  • Biomarkers, Tumor
  • Isocitrate Dehydrogenase
  • IDH1 protein, human