Classification, epidemiology and therapies for testicular germ cell tumours

Int J Dev Biol. 2013;57(2-4):133-9. doi: 10.1387/ijdb.130031nv.

Abstract

Testicular germ cell tumours (TGCT) account for between 1% and 1.5% of male neoplasms and 5% of urological tumours in general. They are classified broadly into Seminoma, which resemble primordial germ cells (PGCs), and Non-Seminoma, which are either undifferentiated (embryonal carcinoma) or differentiated (exhibiting a degree of embryonic (teratoma) or extra-embryonic (yolk sac choriocarcinoma) patterning). We present the current details of the latest classification, epidemiology and treatment aspects of TGCT in the UK in our review.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Male
  • Neoplasms, Germ Cell and Embryonal / classification
  • Neoplasms, Germ Cell and Embryonal / epidemiology*
  • Neoplasms, Germ Cell and Embryonal / therapy*
  • Testicular Neoplasms / classification
  • Testicular Neoplasms / epidemiology*
  • Testicular Neoplasms / therapy*

Supplementary concepts

  • Testicular Germ Cell Tumor