Partek Genomics Suite (Partek GS) is a powerful statistical analysis and interactive visualization software solution designed to analyze single channel oligonucleotide (Affymetrix) and two-color cDNA microarrays, as well as data from other emerging genomic and proteomic technologies. This chapter takes a simple study on obesity and susceptibility to type 2 diabetes and uses it as an example that demonstrates how Partek GS can be used to analyze data arising from a microarray experiment.