ReviewPharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles
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Keywords
Transcription
Screening
Proteomics
Interactome
Pharmacology
Specificity
Cancer
Genomics
Abbreviations
PPID
Protein-protein interaction disruptor
TF
Transcription factor
HMG
High-mobility group
ChIP-seq
Chromatin immunoprecipitation sequencing
GPCR
G protein-coupled receptors
RIME
Rapid immunoprecipitation mass spectrometry of endogenous proteins
NSAID
Nonsteroidal anti-inflammatory drug
AP-MS
Affinity purification-mass spectrometry
RNA-seq
RNA-sequencing
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Published online: 12 March 2015
Copyright © 2015 Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences. Publishing Services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd