Original articleChromosome analysis of 96 uterine leiomyomas☆
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2019, Gynecologic Oncology ReportsCitation Excerpt :This ULMS had many high-risk features including a large size, necrosis, high pathologic grade, myometrial invasion. The karyotypic aberrations including those of chromosomes 7, 12 and 14 and t(7;13)(p11.2; q11.2) noted in this LM has been previously described (Pandis et al., 1991). There was an unbalanced translocation between the long arms of chromosomes 12 and 14 [resulting in dup (12q)], and a derivative chromosome 15 with interstitial deletion and paracentric inversion of the long arm.
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This work was supported by grants from the Swedish Cancer Society and the Ingabritt and Arne Lundberg's Research Foundation.
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Drs. Pandis and Bardi are on leave from the Papanikolaou Research Center, Hellenic Anticancer Institute, Athens, Greece. Their visit to Sweden was made possible by financial support from the Swedish Institute.