Regular ArticleCloning of the Human Interferon-Related Developmental Regulator (IFRD1) Gene Coding for the PC4 Protein, a Member of a Novel Family of Developmentally Regulated Genes☆,☆☆
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Data on molecular characterisation and expression analysis of the interferon-related developmental regulator 2 (IFRD2) gene from red sea bream, Pagrus major
2019, Data in BriefCitation Excerpt :The interferon-related developmental regulator 1 (IFRD1) protein has been reported to play a role in the regulation of inflammatory responses [1]. Also, interferon-related developmental regulator 2 (IFRD2) in mice may be associated with early haematopoiesis after gastrulation and in the hepatic primordium [2]. The open reading frame (ORF) of the PmIFRD2 cDNA was identified from red sea bream injected with S. iniae and consisted of 1308 bp, that encoded 435 amino acids (aa).
Variation in embryonic mortality and maternal transcript expression among Atlantic cod (Gadus morhua) broodstock: A functional genomics study
2014, Marine GenomicsCitation Excerpt :For example, in early rat embryos, high ifrd1 transcript expression along the neural tube suggests that this gene is involved in embryonic neuroblast differentiation (reviewed by Vietor and Huber, 2007). In the embryonic mouse, ifrd1 transcript is expressed in several tissues including developing kidney, lung, and the central nervous system (Buanne et al., 1998). While ifrd1 knockout mice are fertile, they have decreased adult body weight (possibly due to muscle atrophy), altered muscle regeneration and function, and down-regulated muscle-specific genes (Vadivelu et al., 2004; reviewed by Vietor and Huber, 2007).
First report on interferon related developmental regulator-1 from Macrobrachium rosenbergii: Bioinformatic analysis and gene expression
2012, Fish and Shellfish ImmunologyCitation Excerpt :Phylogenetically, MrIRDR-1 is most closely related to IRDR-1 from G. morsitans morsitans. Both belong to a member of a novel family of developmentally regulated genes [26] and they share 54% sequence similarity. Further, MrIRDR-1 is formed sister branch with IRDR-1 from other arthropod C. floridanus and finally clustered together with IRDR-1 from another arthropod H. saltator.
Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells
2012, Food and Chemical ToxicologyPC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-κB
2011, Journal of Biological ChemistryMutations to LmIFRD affect cell wall integrity, development and pathogenicity of the ascomycete Leptosphaeria maculans
2009, Fungal Genetics and Biology
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Sequence data from this article have been deposited with the EMBL Data Library under Accession No. Y10313.
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D. RickwoodD. L. Cockroft
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To whom correspondence should be addressed at the Institute of Neurobiology, National Research Council, Viale Marx 43, 00137 Rome, Italy. Telephone: 39-6-86090290. Fax: 39-6-86090370. E-mail:[email protected].