synergy

Open Access
Extensive DNA Damage and Loss of Cell Viability Occur Synergistically With the Combination of Recombinant Methioninase and Paclitaxel on Pancreatic Cancer Cells which Report DNA-Damage Response in Real Time
SEI MORINAGA, QINGHONG HAN, KOHEI MIZUTA, BYUNG MO KANG, MOTOKAZU SATO, MICHAEL BOUVET, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Cancer Genomics & Proteomics November 2024, 21 (6) 585-590; DOI: https://doi.org/10.21873/cgp.20475
Open Access
The Combination of Methioninase and Ethionine Exploits Methionine Addiction to Selectively Eradicate Osteosarcoma Cells and Not Normal Cells and Synergistically Down-regulates the Expression of C-MYC
YUSUKE AOKI, YUTARO KUBOTA, QINGHONG HAN, NORIYUKI MASAKI, KOYA OBARA, MICHAEL BOUVET, SANT P. CHAWLA, YASUNORI TOME, KOTARO NISHIDA and ROBERT M. HOFFMAN

Cancer Genomics & Proteomics December 2023, 20 (6suppl) 679-685; DOI: https://doi.org/10.21873/cgp.20415

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