PT  - JOURNAL ARTICLE
AU  - Weidong Zhou
AU  - Lance A. Liotta
AU  - Emanuel F. Petricoin
TI  - Cancer Metabolism: What we Can Learn from Proteomic Analysis by Mass Spectrometry
DP  - 2012 Nov 01
TA  - Cancer Genomics - Proteomics
PG  - 373--381
VI  - 9
IP  - 6
4099  - http://cgp.iiarjournals.org/content/9/6/373.short
4100  - http://cgp.iiarjournals.org/content/9/6/373.full
SO  - Cancer Genomics Proteomics2012 Nov 01; 9
AB  - A variety of genomic and proteomic tools have been used to study cancer metabolism and metabolomics in order to understand how cancer cells survive in their environment. Throughout the past decade, mass spectrometry has been routinely used for large-scale protein identification of complex biological mixtures. In this review, we discuss some recent developments in cancer metabolism by proteomic analysis using mass spectrometric techniques, focusing on pyruvate kinase, L-lactate dehydrogenase, Warburg effect, glutamine metabolism and oxidative stress.