PT - JOURNAL ARTICLE AU - Juliana Noguti AU - Carolina Foot Gomes De Moura AU - Gustavo Protasio Pacheco De Jesus AU - Victor Hugo Pereira Da Silva AU - Thais Ayako Hossaka AU - Celina Tijuko Fujiyama Oshima AU - Daniel Araki Ribeiro TI - Metastasis from Oral Cancer: An Overview DP - 2012 Sep 01 TA - Cancer Genomics - Proteomics PG - 329--335 VI - 9 IP - 5 4099 - http://cgp.iiarjournals.org/content/9/5/329.short 4100 - http://cgp.iiarjournals.org/content/9/5/329.full SO - Cancer Genomics Proteomics2012 Sep 01; 9 AB - Oral cancer is a common neoplasm worldwide. Its incidence and mortality have also increased over the past decades. It is characterized by poor prognosis and a low survival rate despite sophisticated surgical and radiotherapeutic modalities. Metastasis of oral cancer is a complex process involving detachment of cells from tumor tissue, regulation of cell motility and invasion, proliferation and evasion through the lymphatic system or blood vessels. In this review, we will focus on the current knowledge in metastasis from oral cancer regarding facts, such as incidence; stage, histopathology and grade of primary tumor; clinical manifestations; diagnosis; and treatment. Certainly, such information will contribute to the understanding of oral cancer pathogenesis.