RT Journal Article SR Electronic T1 Breast Cancer Metastasis JF Cancer Genomics - Proteomics JO Cancer Genomics Proteomics FD International Institute of Anticancer Research SP 311 OP 320 VO 9 IS 5 A1 Olivia Jane Scully A1 Boon-Huat Bay A1 George Yip A1 Yingnan Yu YR 2012 UL http://cgp.iiarjournals.org/content/9/5/311.abstract AB Breast cancer metastasis accounts for the majority of deaths from breast cancer. Detection of breast cancer metastasis at the earliest stage is important for the management and prediction of breast cancer progression. Emerging techniques using the analysis of circulating tumor cells show promising results in predicting and identifying the early stages of breast cancer metastasis in patients. Additionally, a deeper understanding of the metastatic cascade in breast cancer will be critical for developing therapeutic interventions to combat breast cancer metastasis. In this review, the current and novel methods for detection of breast cancer metastasis, as well as the mechanisms involved in metastasis and the treatment of breast cancer metastasis, are discussed.