PT - JOURNAL ARTICLE AU - PANTIPA SUBHASITANONT AU - CHANTRAGAN SRISOMSAP AU - PHAIBUL PUNYARIT AU - JISNUSON SVASTI TI - Proteomic Studies of Galectin-3 Expression in Human Thyroid Diseases by Immunodetection DP - 2006 Nov 01 TA - Cancer Genomics - Proteomics PG - 389--394 VI - 3 IP - 6 4099 - http://cgp.iiarjournals.org/content/3/6/389.short 4100 - http://cgp.iiarjournals.org/content/3/6/389.full SO - Cancer Genomics Proteomics2006 Nov 01; 3 AB - Galectin-3 expression in thyroid diseases was studied by 1-DE immunoblotting. Expression was markedly elevated in thyroid papillary carcinoma, compared to follicular adenoma, follicular carcinoma or non-neoplastic diseases. Galectin-3 expression was also elevated in malignant cancers of bone, breast, colon, esophagus, larynx, lung and ovary. Four cases of thyroid papillary carcinoma with metastasis gave 2-3 bands on 1-DE immunoblotting. 2-DE immunoblotting of gelectin-3 showed 3 dark spots with MW/pI 32.9/8.29, 31.0/8.40 and 30.0/8.40 and 2 light spots.