<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">KIM, EOJIN</style></author><author><style face="normal" font="default" size="100%">KIM, HYUNJIN</style></author><author><style face="normal" font="default" size="100%">YEO, MIN-KYUNG</style></author><author><style face="normal" font="default" size="100%">KIM, CHUL HWAN</style></author><author><style face="normal" font="default" size="100%">KIM, JOO YOUNG</style></author><author><style face="normal" font="default" size="100%">PARK, SUNGSOO</style></author><author><style face="normal" font="default" size="100%">KIM, HYUN-SOO</style></author><author><style face="normal" font="default" size="100%">CHAE, YANG-SEOK</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Identification of a Novel Long Non-coding RNA, &lt;em&gt;lnc-ATMIN-4:2&lt;/em&gt;, and its Clinicopathological and Prognostic Significance in Advanced Gastric Cancer</style></title><secondary-title><style face="normal" font="default" size="100%">Cancer Genomics - Proteomics</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2022-11-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">761-772</style></pages><doi><style  face="normal" font="default" size="100%">10.21873/cgp.20358</style></doi><volume><style face="normal" font="default" size="100%">19</style></volume><issue><style face="normal" font="default" size="100%">6</style></issue><abstract><style  face="normal" font="default" size="100%">Background/Aim: Long non-coding RNAs (lncRNAs) are emerging as significant regulators of gene expression and a novel promising biomarker for cancer diagnosis and prognosis. This study identified a novel, differentially expressed lncRNA in advanced gastric cancer (AGC), Inc-ATMIN-4:2, and evaluated its clinicopathological and prognostic significance. Patients and Methods: Whole transcriptome sequencing was performed to identify differentially expressed lncRNAs in AGC tissue samples. We also analyzed lnc-ATMIN-4:2 expression in 317 patients with AGC using RNA in situ hybridization. Results: High (&gt;30 dots) lnc-ATMIN-4:2 expression significantly correlated with younger age, poorly differentiated histology, diffuse type, deeper invasion depth, perineural invasion, lymph node metastasis, and higher stage group. In addition, high lnc-ATMIN-4:2 expression was significantly associated with worse overall survival in patients with AGC. Conclusion: This study elucidated the significance of lncRNAs in AGC and indicated the value of lnc-ATMIN-4:2 expression as a predictive biomarker for the overall survival of patients with AGC.</style></abstract></record></records></xml>