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Transcriptome-based Deep Learning Model for Predicting Gemcitabine and Cisplatin Chemotherapy Response in Urothelial Carcinoma: Development and External Validation

JUWON KANG, HYUN JUNG LEE, SANG-BO OH, JONG KIL NAM, TAE UN KIM, HWASEONG RYU, YONG KAN KI, JIHOON KANG, YI RANG KIM, JEONG HOON LEE, JUNJEONG CHOI, YUN JEONG HONG and KWONOH PARK
Cancer Genomics & Proteomics May 2026, 23 (3) 546-557; DOI: https://doi.org/10.21873/cgp.20589

Article Information

vol. 23 no. 3 546-557
DOI 
https://doi.org/10.21873/cgp.20589
PMID 
42055629
Published By 
International Institute of Anticancer Research
Print ISSN 
1109-6535
Online ISSN 
1790-6245
History 
  • Received January 14, 2026
  • Revision received February 15, 2026
  • Accepted February 24, 2026
  • Published online April 29, 2026.
Copyright & License 
Copyright © 2026 The Author(s). Published by the International Institute of Anticancer Research. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY-NC-ND) 4.0 international license (https://creativecommons.org/licenses/by-nc-nd/4.0).

Author Information

  1. JUWON KANG1,2,*,
  2. HYUN JUNG LEE3,*,
  3. SANG-BO OH4,
  4. JONG KIL NAM5,
  5. TAE UN KIM6,
  6. HWASEONG RYU6,
  7. YONG KAN KI7,
  8. JIHOON KANG1,
  9. YI RANG KIM1,
  10. JEONG HOON LEE8,
  11. JUNJEONG CHOI2,
  12. YUN JEONG HONG9 and
  13. KWONOH PARK3,10⇑
  1. 1ONCOCROSS Co., Ltd., Seoul, Republic of Korea;
  2. 2Yonsei Institute of Pharmaceutical Sciences, College of Pharmacy, Yonsei University, Incheon, Republic of Korea;
  3. 3Department of Pathology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea;
  4. 4Medical Oncology and Hematology, Department of Internal medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea;
  5. 5Department of Urology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea;
  6. 6Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea;
  7. 7Department of Radiation Oncology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea;
  8. 8Department of Radiology, Stanford University School of Medicine, Stanford, CA, U.S.A.;
  9. 9Department of Neurology, Uijeongbu St. Mary’s Hospital, Catholic University of Korea, Seoul, Republic of Korea;
  10. 10Division of Hematology & Medical Oncology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Republic of Korea
  1. Kwonoh Park, Division of Hematology & Medical Oncology, Department of Internal Medicine, Dongguk University Ilsan Hospital, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 10326, Republic of Korea. Tel: +82 0319617096, e-mail: parkkoh{at}daum.net

  1. ↵* These Authors contributed equally to this work.

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Transcriptome-based Deep Learning Model for Predicting Gemcitabine and Cisplatin Chemotherapy Response in Urothelial Carcinoma: Development and External Validation
JUWON KANG, HYUN JUNG LEE, SANG-BO OH, JONG KIL NAM, TAE UN KIM, HWASEONG RYU, YONG KAN KI, JIHOON KANG, YI RANG KIM, JEONG HOON LEE, JUNJEONG CHOI, YUN JEONG HONG, KWONOH PARK
Cancer Genomics & Proteomics May 2026, 23 (3) 546-557; DOI: 10.21873/cgp.20589
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