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Desert Hedgehog Down-regulation Mediates Inhibition of Proliferation by γ-Glutamylcyclotransferase Knockdown in Murine Glioblastoma Stem Cells

MASAYA MORI, HIROMI II, MITSUGU FUJITA, KOZUE NOSE, AYAKO SHIMADA, RISA SHIRAKI, YUHI SONE, CHIAMI MOYAMA, KEIKO TANIGUCHI and SUSUMU NAKATA
Cancer Genomics & Proteomics September 2024, 21 (5) 474-484; DOI: https://doi.org/10.21873/cgp.20465
MASAYA MORI
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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HIROMI II
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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MITSUGU FUJITA
2Center for Medical Education and Clinical Training, Kindai University Faculty of Medicine, Osaka-Sayama, Japan;
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KOZUE NOSE
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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AYAKO SHIMADA
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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RISA SHIRAKI
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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YUHI SONE
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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CHIAMI MOYAMA
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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KEIKO TANIGUCHI
3Department of Drug Discovery Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
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SUSUMU NAKATA
1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
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  • For correspondence: snakata{at}mb.kyoto-phu.ac.jp
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Article Information

vol. 21 no. 5 474-484
DOI 
https://doi.org/10.21873/cgp.20465
PMID 
39191500

Published By 
International Institute of Anticancer Research
Print ISSN 
1109-6535
Online ISSN 
1790-6245
History 
  • Received May 9, 2024
  • Revision received July 12, 2024
  • Accepted July 19, 2024
  • Published online August 27, 2024.

Copyright & License 
Copyright © 2024 The Author(s). Published by the International Institute of Anticancer Research. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY-NC-ND) 4.0 international license (https://creativecommons.org/licenses/by-nc-nd/4.0).

Author Information

  1. MASAYA MORI1,
  2. HIROMI II1,
  3. MITSUGU FUJITA2,
  4. KOZUE NOSE1,
  5. AYAKO SHIMADA1,
  6. RISA SHIRAKI1,
  7. YUHI SONE1,
  8. CHIAMI MOYAMA1,*,
  9. KEIKO TANIGUCHI3 and
  10. SUSUMU NAKATA1⇑
  1. 1Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Kyoto, Japan;
  2. 2Center for Medical Education and Clinical Training, Kindai University Faculty of Medicine, Osaka-Sayama, Japan;
  3. 3Department of Drug Discovery Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
  1. Correspondence to: Susumu Nakata, MD, Ph.D., Laboratory of Clinical Oncology, Kyoto Pharmaceutical University, Misasagi-Nakauchicho 5, Yamashina-ku, Kyoto 607-8414, Japan. Tel: +81 755954719, e-mail: snakata{at}mb.kyoto-phu.ac.jp
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Cancer Genomics - Proteomics: 21 (5)
Cancer Genomics & Proteomics
Vol. 21, Issue 5
September-October 2024
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Desert Hedgehog Down-regulation Mediates Inhibition of Proliferation by γ-Glutamylcyclotransferase Knockdown in Murine Glioblastoma Stem Cells
MASAYA MORI, HIROMI II, MITSUGU FUJITA, KOZUE NOSE, AYAKO SHIMADA, RISA SHIRAKI, YUHI SONE, CHIAMI MOYAMA, KEIKO TANIGUCHI, SUSUMU NAKATA
Cancer Genomics & Proteomics Sep 2024, 21 (5) 474-484; DOI: 10.21873/cgp.20465

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Desert Hedgehog Down-regulation Mediates Inhibition of Proliferation by γ-Glutamylcyclotransferase Knockdown in Murine Glioblastoma Stem Cells
MASAYA MORI, HIROMI II, MITSUGU FUJITA, KOZUE NOSE, AYAKO SHIMADA, RISA SHIRAKI, YUHI SONE, CHIAMI MOYAMA, KEIKO TANIGUCHI, SUSUMU NAKATA
Cancer Genomics & Proteomics Sep 2024, 21 (5) 474-484; DOI: 10.21873/cgp.20465
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Keywords

  • γ-Glutamylcyclotransferase
  • GGCT
  • desert hedgehog
  • the hedgehog pathway
  • glioblastoma stem cells
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